Harahap Muhammad Irvanie Rama, Soetikno Rista D, Anwary Farhan
Department of Radiology, Faculty of Medicine, Universitas Padjadjaran - Hasan Sadikin National General Hospital, Bandung, Indonesia.
Eur J Radiol Open. 2022 Dec 15;10:100469. doi: 10.1016/j.ejro.2022.100469. eCollection 2023.
To determine the relationship between neutrophils count in cerebrospinal fluid and cerebral infarction in head magnetic resonance imaging (MRI) on patients with tuberculous meningitis.
A diagnostic study was done on patients with tuberculous meningitis (TBM) who underwent head MRI examination and cerebrospinal fluid analysis at Dr. Hasan Sadikin General Hospital from January 2015 to September 2016. TBM was diagnosed by Mycobacterium tuberculosis isolation from cerebrospinal fluid. Cut-off value of neutrophil count was determined using receiver operating characteristics (ROC) curve. Conformity test was done using Kappa test.
Thirty seven subjects were recruited in this study. Higher neutrophil count in CSF was observed on subjects with cerebral infarction (p < 0.05). Cut-off value of neutrophil count in CSF was determined as > 41 %. There was a moderate conformity between higher neutrophil count in CSF and cerebral infarction appearance in MRI (p < 0.05, Kappa score 0.529).
Higher neutrophil count was associated with the appearance of cerebral infarct in head MRI on adult patients with tuberculous meningitis.
确定结核性脑膜炎患者脑脊液中中性粒细胞计数与头部磁共振成像（MRI）显示的脑梗死之间的关系。
对2015年1月至2016年9月在哈桑·萨迪金综合医院接受头部MRI检查和脑脊液分析的结核性脑膜炎（TBM）患者进行了一项诊断性研究。通过从脑脊液中分离出结核分枝杆菌来诊断TBM。使用受试者工作特征（ROC）曲线确定中性粒细胞计数的临界值。使用Kappa检验进行一致性检验。
本研究招募了37名受试者。在有脑梗死的受试者中观察到脑脊液中中性粒细胞计数较高（p < 0.05）。脑脊液中中性粒细胞计数的临界值确定为> 41%。脑脊液中较高的中性粒细胞计数与MRI中脑梗死表现之间存在中度一致性（p < 0.05，Kappa评分0.529）。
在患有结核性脑膜炎的成年患者中，较高的中性粒细胞计数与头部MRI中脑梗死的出现有关。
