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常规超声及弹性成像技术建立兔坐骨神经挤压伤模型的研究。

Study on the Crush Injury Model of the Sciatic Nerve in Rabbits by Conventional Ultrasound and Elastography.

机构信息

Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324, Jingwu Road, Jinan 250021, Shandong, China.

Department of Hand-Foot surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No.324, Jingwu Road, Jinan 250021, Shandong, China.

出版信息

Curr Med Imaging. 2023;19(7):764-769. doi: 10.2174/1573405619666221228152506.

Abstract

BACKGROUND

The crush injury model of the sciatic nerve in rabbits is a common nerve injury model, but there is little literature on the evaluation of nerve stiffness by ultrasound elastography.

PURPOSE

To explore the value of ultrasound elastography in diagnosing crush injury of the sciatic nerve in rabbits.

MATERIALS AND METHODS

Forty cases of crush injury model of the sciatic nerve in rabbits were examined by conventional ultrasound and elastography. The sonographic manifestations and stiffness of the model were analyzed, and the regularity of nerve injury with time was summarized.

RESULTS

Ultrasound could clearly show the location, range, and thickness of the injured nerve in this model. The thickness of the injured area reached a peak in the 2nd week and returned to normal thickness in the 8th week. The nerve stiffness of the injured area increased gradually with time.

CONCLUSION

Conventional ultrasound combined with elastography can comprehensively and quantitatively evaluate the morphological changes and mechanical properties of the injured sciatic nerve in rabbits, which may be of great significance to the repair and rehabilitation of peripheral nerve crush injuries.

摘要

背景

兔坐骨神经挤压伤模型是一种常见的神经损伤模型,但关于超声弹性成像评估神经硬度的文献较少。

目的

探讨超声弹性成像在诊断兔坐骨神经挤压伤中的价值。

材料与方法

对 40 例兔坐骨神经挤压伤模型进行常规超声和弹性成像检查。分析模型的超声表现和硬度,总结神经损伤随时间的变化规律。

结果

超声能清晰显示该模型中损伤神经的位置、范围和厚度。损伤区的厚度在第 2 周达到峰值,第 8 周恢复正常厚度。损伤区的神经硬度随时间逐渐增加。

结论

常规超声结合弹性成像可全面、定量地评估兔坐骨神经损伤后的形态学变化和力学特性,这对于周围神经挤压伤的修复和康复可能具有重要意义。

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