Shalat S L, Seltzer B, Pidcock C, Baker E L
Department of Epidemiology, Harvard School of Public Health, Boston, MA.
Neurology. 1987 Oct;37(10):1630-3. doi: 10.1212/wnl.37.10.1630.
A case-control study was conducted to assess personal and family medical history and the appearance of Alzheimer's disease. We compared 98 men with clinically diagnosed Alzheimer's disease and 162 controls, matched by sex, year of birth, and town of residence. Family history of dementia and personal history of depression were more frequent in patients. The number of cigarettes smoked was greater in cases.
开展了一项病例对照研究,以评估个人及家族病史与阿尔茨海默病的发病情况。我们比较了98名临床诊断为阿尔茨海默病的男性与162名对照者,后者在性别、出生年份和居住城镇方面与之匹配。患者中痴呆家族史和抑郁症个人史更为常见。病例组的吸烟量更大。