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一例源自阔韧带的黏液样脂肪肉瘤罕见病例报告。

A rare case report of a myxoid liposarcoma arising from the broad ligament.

作者信息

Sassi Farah, Sahraoui Ghada, Charfi Lamia, Ines Zemni, Mrad Karima, Doghri Raoudha

机构信息

Pathology Department, Salah Azaiez Institute, Tunis, Tunisia.

Research Laboratory LR21SP01, Salah Azaiez Institute Tunis, Tunisia.

出版信息

Rare Tumors. 2022 Dec 23;14:20363613221148839. doi: 10.1177/20363613221148839. eCollection 2022.

DOI:10.1177/20363613221148839
PMID:36582402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9793064/
Abstract

Myxoid liposarcoma (MLPS) is the second most prevalent subtype of liposarcoma. It is usually found in the deep tissues of the lower limbs and rarely in gynecologic tract. Herein we present the second case in the English literature of a primary MLPS arising from the broad ligament which was thought to be a borderline ovarian tumor. The aim is to discuss its clinical and pathological characteristics. A 42-year-old woman presented with pelvic pain for the last 6 months. Magnetic resonance imaging was not specific. She underwent a surgical resection of the tumor mass, and pathological examination confirmed the diagnosis of MLPS deriving from the broad ligament. She received radiotherapy and the patient is doing well at 3 months follow-up. The clinical aspects, pathological diagnosis, prognosis, and therapy approach of broad ligament MLPS are all poorly understood. Complete surgical resection with or without radiotherapy is the mainstay of treatment in located MLPS.

摘要

黏液样脂肪肉瘤(MLPS)是脂肪肉瘤中第二常见的亚型。它通常发生于下肢深部组织,很少见于生殖道。在此,我们报告英文文献中第二例起源于阔韧带的原发性MLPS病例,该病例最初被认为是交界性卵巢肿瘤。目的是讨论其临床和病理特征。一名42岁女性在过去6个月出现盆腔疼痛。磁共振成像结果不具有特异性。她接受了肿瘤肿块的手术切除,病理检查确诊为起源于阔韧带的MLPS。她接受了放疗,在3个月的随访中患者情况良好。阔韧带MLPS的临床特征、病理诊断、预后及治疗方法均了解甚少。对于局限性MLPS,完整手术切除联合或不联合放疗是主要治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/9793064/4b92e4343b74/10.1177_20363613221148839-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/9793064/146113e68472/10.1177_20363613221148839-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/9793064/81f85e36f1d5/10.1177_20363613221148839-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/9793064/8afa3d1046ad/10.1177_20363613221148839-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/9793064/4b92e4343b74/10.1177_20363613221148839-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/9793064/146113e68472/10.1177_20363613221148839-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/9793064/81f85e36f1d5/10.1177_20363613221148839-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/9793064/8afa3d1046ad/10.1177_20363613221148839-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/9793064/4b92e4343b74/10.1177_20363613221148839-fig4.jpg

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本文引用的文献

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Primary High-Grade Myxoid Liposarcoma of the Extremities: Prognostic Factors and Metastatic Pattern.肢体原发性高级别黏液样脂肪肉瘤:预后因素与转移模式
Cancers (Basel). 2022 May 27;14(11):2657. doi: 10.3390/cancers14112657.
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Primary dedifferentiated Liposarcoma of vagina: a first case report.阴道原发性去分化脂肪肉瘤:首例报告。
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Primary low grade myxoid liposarcoma of the ovary: A case report and review of literature.卵巢原发性低级别黏液样脂肪肉瘤:一例报告并文献复习
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Primary myxoid liposarcoma of the pelvis: An unusual location.骨盆原发性黏液样脂肪肉瘤:一个不寻常的部位。
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A comprehensive review of the current evidence for trabectedin in advanced myxoid liposarcoma.探讨 trabectedin 在高级黏液样脂肪肉瘤中的现有证据的全面综述。
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Myxoid Liposarcoma: Prognostic Factors and Metastatic Pattern in a Series of 148 Patients Treated at a Single Institution.黏液样脂肪肉瘤:在一家机构接受治疗的148例患者的预后因素和转移模式
Int J Surg Oncol. 2018 May 16;2018:8928706. doi: 10.1155/2018/8928706. eCollection 2018.
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Spectrum of mucin-producing neoplastic conditions of the abdomen and pelvis: cross-sectional imaging evaluation.腹部和骨盆产黏液性肿瘤性病变的范围:横断面成像评估。
World J Gastroenterol. 2011 Nov 21;17(43):4757-71. doi: 10.3748/wjg.v17.i43.4757.