Augsburger J J, Roth S E, Magargal L E, Shields J A
Oncology Service, Wills Eye Hospital, Philadelphia, Pennsylvania 19107.
Ophthalmic Surg. 1987 Aug;18(8):589-93.
We present preliminary findings on the effectiveness of panretinal photocoagulation in preventing neovascular glaucoma in eyes with radiation-induced ocular ischemia. Our study group consisted of 20 patients who developed radiation-induced ocular ischemia following cobalt-60 plaque radiotherapy for a choroidal or ciliary body melanoma. Eleven of the 20 patients were treated by panretinal photocoagulation shortly after the diagnosis of ocular ischemia, but nine patients were left untreated. In this non-randomized study, the rate of development of neovascular glaucoma was significantly lower (p = 0.024) for the 11 photocoagulated patients than for the nine who were left untreated.
我们展示了关于全视网膜光凝术在预防因辐射诱导性眼部缺血而导致新生血管性青光眼方面有效性的初步研究结果。我们的研究组由20名患者组成,这些患者在接受钴-60敷贴放疗治疗脉络膜或睫状体黑色素瘤后出现了辐射诱导性眼部缺血。20名患者中有11名在眼部缺血诊断后不久接受了全视网膜光凝术治疗,但有9名患者未接受治疗。在这项非随机研究中,11名接受光凝术治疗的患者发生新生血管性青光眼的比率显著低于9名未接受治疗的患者(p = 0.024)。