Predatu Răzvan, Voinescu Bogdan I, David Daniel O, Maffei Antonio, Nechifor Ruben E, Gentili Claudio
Department of Clinical Psychology and Psychotherapy, Babeş-Bolyai University, Cluj-Napoca, Romania; International Institute for the Advanced Studies of Psychotherapy and Applied Mental Health, Babeş-Bolyai University, Cluj-Napoca, Romania.
Department of Clinical Psychology and Psychotherapy, Babeş-Bolyai University, Cluj-Napoca, Romania; International Institute for the Advanced Studies of Psychotherapy and Applied Mental Health, Babeş-Bolyai University, Cluj-Napoca, Romania; Bristol Royal Infirmary, University Hospitals Bristol NHS Foundation Trust, Bristol, UK; Centre for Academic Mental Health, University of Bristol, Bristol, UK.
Sleep Med. 2023 Jan;101:561-569. doi: 10.1016/j.sleep.2022.11.033. Epub 2022 Dec 5.
The aim of the current study was to investigate whether the experience of insomnia symptoms per se and symptoms of insomnia due to stress are associated with an increased brain response to the presentation of emotional faces. In addition, we also examined whether the effect of these sleep difficulties on emotional reactivity at the brain level depends on the experience of emotion regulation (ER) difficulties. The current sample consisted of 37 individuals (20 females, 17 males) selected from a larger group of 120 respondents who completed a survey about sleep problems and ER difficulties. Our results indicate that the tendency to experience stress-related insomnia symptoms but not insomnia symptoms per se modulates brain responses to emotional facial expressions, especially in areas of the parietal cortex, insula, and surrounding opercular voxels. Furthermore, difficulties in ER might play an important role, as the effect of stress-related insomnia symptoms on most of these brain regions disappears when controlling for difficulties in ER. However, an effect in the insula was maintained during the presentation of angry faces, suggesting that stress-related insomnia symptoms may increase the brain response to anger in the insula relatively independent from difficulties in ER. These findings suggest that individuals affected by stress-related insomnia symptoms show an enhanced brain response when presented with emotional stimuli (either positive or negative) in brain areas associated with hyperarousal, which could represent a possible ER deficit in these individuals. Thus, interventions that focus on targeting ER difficulties might be effective in reducing the hyperarousal state in individuals affected by stress-related insomnia symptoms.
本研究的目的是调查失眠症状本身以及应激性失眠症状是否与大脑对情绪面孔呈现的反应增强有关。此外，我们还研究了这些睡眠困难对大脑水平情绪反应性的影响是否取决于情绪调节（ER）困难的经历。当前样本由37名个体（20名女性，17名男性）组成，他们是从120名完成了关于睡眠问题和ER困难调查 的受访者中挑选出来的。我们的结果表明，经历与应激相关的失眠症状而非失眠症状本身的倾向会调节大脑对情绪面部表情的反应，尤其是在顶叶皮质、脑岛及周围的岛盖体素区域。此外，ER困难可能起重要作用，因为在控制ER困难后，与应激相关的失眠症状对这些大脑区域中大多数区域的影响消失了。然而，在呈现愤怒面孔期间，脑岛中的效应仍然存在，这表明与应激相关的失眠症状可能相对独立于ER困难而增加大脑对脑岛中愤怒情绪的反应。这些发现表明，受与应激相关的失眠症状影响的个体在与过度唤醒相关的脑区中面对情绪刺激（无论是积极的还是消极的）时，大脑反应增强，这可能代表了这些个体中可能存在的ER缺陷。因此，专注于解决ER困难的干预措施可能有效地减轻受与应激相关的失眠症状影响的个体的过度唤醒状态。
