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通过基因组编辑加速森林树木的驯化:进展与展望。

Accelerating wood domestication in forest trees through genome editing: Advances and prospects.

机构信息

Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium; VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.

Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium; VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.

出版信息

Curr Opin Plant Biol. 2023 Feb;71:102329. doi: 10.1016/j.pbi.2022.102329. Epub 2022 Dec 29.

DOI:10.1016/j.pbi.2022.102329
PMID:36586396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7614060/
Abstract

The high economic value of wood requires intensive breeding towards multipurpose biomass. However, long breeding cycles hamper the fast development of novel tree varieties that have improved biomass properties, are tolerant to biotic and abiotic stresses, and resilient to climate change. To speed up domestication, the integration of conventional breeding and new breeding techniques is needed. In this review, we discuss recent advances in genome editing and Cas-DNA-free genome engineering of forest trees, and briefly discuss how multiplex editing combined with multi-omics approaches can accelerate the genetic improvement of forest trees, with a focus on wood.

摘要

木材的高经济价值需要朝着多用途生物质进行集约化培育。然而,漫长的培育周期阻碍了新型树木品种的快速发展,这些新型树木品种具有改良的生物质特性,能够耐受生物和非生物胁迫,并且对气候变化具有弹性。为了加快驯化进程,需要将常规育种与新的育种技术相结合。在这篇综述中,我们讨论了林木基因组编辑和 Cas-DNA 免费基因组工程的最新进展,并简要讨论了如何将多重编辑与多组学方法相结合,以加速林木的遗传改良,重点是木材。

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