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抗肥胖策略对健康和疾病状态下脑功能的影响:综述

Influence of anti-obesity strategies on brain function in health and review: A review.

作者信息

Souza Keila Rufatto de, Engel Nicole Alessandra, Costa Ana Beatriz, Soares Hevylin Jacintho, Bressan Catarina Barbosa Chaves, Oliveira Mariana Pacheco de, Dela Vedova Larissa Marques, Silva Larissa Espindola da, Mendes Talita Farias, Silva Mariella Reinol da, Rezin Gislaine Tezza

机构信息

Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina at Tubarão, Santa Catarina, Brazil.

Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Postgraduate Program in Health Sciences, University of Southern Santa Catarina at Tubarão, Santa Catarina, Brazil.

出版信息

Neurochem Int. 2023 Feb;163:105468. doi: 10.1016/j.neuint.2022.105468. Epub 2022 Dec 30.

Abstract

The aim of this review was to investigate in the literature the application of strategies such as low carbohydrate diet (LCD), ketogenic diet (KD) and intermittent fasting (IF) and their effects on the CNS. We performed a narrative review of the literature. The search was specifically carried out in PubMed, selecting articles in English, which had the following keywords: obesity, central nervous system, low carb diet, ketogenic diet and intermittent fasting, using the narrative review methodology. The studies found show that the benefits of the LCD, KD and IF strategies, at the CNS level, have a strong influence on the mechanisms of hunger and satiety, as well as on the reduction of food reward and show improvement in memory and mood influenced by the interventions.

摘要

本综述的目的是在文献中研究低碳水化合物饮食(LCD)、生酮饮食(KD)和间歇性禁食(IF)等策略的应用及其对中枢神经系统的影响。我们对文献进行了叙述性综述。具体在PubMed中进行检索,选择英文文章,使用叙述性综述方法,关键词为:肥胖、中枢神经系统、低碳水化合物饮食、生酮饮食和间歇性禁食。所发现的研究表明,LCD、KD和IF策略在中枢神经系统层面的益处,对饥饿和饱腹感机制有强烈影响,同时能减少食物奖赏,并显示出受干预影响的记忆和情绪有所改善。

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