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临床环境中基于互联网的暴食症认知行为疗法:一项为期一年随访的随机试验结果

Internet-based cognitive behavioral therapy for bulimic eating disorders in a clinical setting: Results from a randomized trial with one-year follow-up.

作者信息

Högdahl Louise, Birgegård Andreas, Norring Claes, de Man Lapidoth Joakim, Franko Mikael Andersson, Björck Caroline

机构信息

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

Centre for Psychiatry Research, Stockholm Health Care Services, Stockholm, Sweden.

出版信息

Internet Interv. 2022 Dec 21;31:100598. doi: 10.1016/j.invent.2022.100598. eCollection 2023 Mar.

Abstract

BACKGROUND

Those who suffer from eating disorders often experience serious impairment in quality of life and the majority never receive treatment. Treatment availability may be increased by implementing methods that demand less resources and are more easy accessible such as internet-based treatments, but knowledge about their effects is still insufficient. The study evaluated effects of two types of internet-based cognitive behavioral therapy and a structured day patient program, the latter being a standard treatment at an eating disorder clinic at the time for the study.

METHODS

150 participants with bulimic eating disorders randomized to two types of internet based treatments (one pure online treatment and one based on a self-help guide in book-format) or an intensive 16-week day patient program. The number of participants that started treatment was 120 of which 98 in internet treatment and 22 in the day program. Outcome assessments were carried out at baseline, post treatment, and at one-year follow-up.

RESULTS

All treatments were associated with significantly improved eating disorder pathology, self-image, and clinical impairment. Although the day program generally showed larger effects, only one significant difference found was in diagnostic remission post treatment; 51 % of the participant was in remission in internet treatment and 88 % in the day program. At one-year follow-up, participants in the internet treatments had continued to improve, whereas in the day patient program the effect sustained. Internet treatment had a 36 % drop out rate, there were no dropouts found in the day program.

CONCLUSIONS

All treatments were comparable in effect at follow-up, suggesting that internet treatment is a conceivable alternative to standard treatment. Internet treatment in a book-based format was also equally effective as a pure online format. Internet delivered cognitive behavioral treatment forms can make important contributions to achieve increased access to treatment for patients with bulimic eating disorders. Future research and clinical implications for internet delivered treatments in eating disorder services are discussed.

CLINICAL TRIAL REGISTRATION

ISRCTN registry https://www.isrctn.com/ISRCTN44999017. The study was registered retrospectively.

摘要

背景

饮食失调患者的生活质量往往受到严重损害,且大多数人从未接受过治疗。通过采用资源需求较少且更容易获得的方法,如基于互联网的治疗,可以提高治疗的可及性,但关于其效果的知识仍然不足。该研究评估了两种基于互联网的认知行为疗法和一个结构化日间住院项目的效果,后者在研究期间是一家饮食失调诊所的标准治疗方法。

方法

150名患有暴食症的参与者被随机分配到两种基于互联网的治疗(一种是纯在线治疗,另一种是基于书本形式的自助指南)或一个为期16周的强化日间住院项目。开始治疗的参与者有120名,其中98名接受互联网治疗,22名接受日间项目治疗。在基线、治疗后和一年随访时进行结果评估。

结果

所有治疗均与饮食失调病理、自我形象和临床损害的显著改善相关。尽管日间项目总体上显示出更大的效果,但仅发现一个显著差异在于治疗后诊断缓解情况;互联网治疗中有51%的参与者缓解,日间项目中有88%的参与者缓解。在一年随访时,接受互联网治疗的参与者持续改善,而日间住院项目的效果得以维持。互联网治疗的退出率为36%,日间项目未发现退出者。

结论

随访时所有治疗在效果上具有可比性,表明互联网治疗是标准治疗的一种可行替代方案。基于书本形式的互联网治疗与纯在线形式同样有效。基于互联网的认知行为治疗形式可为增加暴食症患者的治疗可及性做出重要贡献。讨论了饮食失调服务中基于互联网治疗的未来研究和临床意义。

临床试验注册

ISRCTN注册库https://www.isrctn.com/ISRCTN44999017。该研究为回顾性注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1423/9801110/937bc9696c59/gr1.jpg

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