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围产期注射多种维生素和硒-维生素 E(α-生育酚)合剂对产后临床发现、血清甾体、犊牛和胎盘重量以及奶抗氧化生物标志物变化的比较研究在雌性单峰驼中。

Comparative study of efficacy of prepartum injection of multivitamins and selenium- vitamin E (ά-tocopherol)-combination on post-partum clinical findings, serum steroids, calf and placental weights, and milk antioxidant biomarkers changes in female dromedary camel.

机构信息

Division of Internal Medicine, Department of Animal Medicine, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.

Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.

出版信息

Open Vet J. 2022 Sep-Oct;12(5):657-667. doi: 10.5455/OVJ.2022.v12.i5.10. Epub 2022 Sep 13.

DOI:10.5455/OVJ.2022.v12.i5.10
PMID:36589409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9789776/
Abstract

BACKGROUND

All concentrates given to camels were enriched in selenium (Se) in selenite form. The impacts of Se supplementation on lactating female health, milk, and Se/antioxidant statuses received no research interest.

AIM

The current study aimed to compare the efficacy of long-term prepartum injection of Se-vitamin E combination and multivitamins on maternal post-calving clinical findings, serum steroid hormones, milk antioxidants, milk somatic cell count (SCC) status, calf body weight, placental weight (PW), and vaginal wash isolates.

METHODS

From three equal groups of postpartum she-camels ( = 45), one group received no treatment and served as control group (Cont.; = 15). For 3 months prepartum, one group had received a combination of vitamin E (ά-tocopherol) and Se (VitE-Se-; = 15), and the third one received multivitamins (Multi-; = 15). All dams were subjected to clinical and laboratory assays including milk total antioxidant capacity (TAC), Se, vitamin E, and milk SCC on Days 14, 21, and 28 post-calving. Steroid hormones and calf and PW were estimated at birth (Day 0).

RESULTS

The study reported higher efficacy of Se-vitamin E combination comparing with that of multivitamins as a long-term prepartum injection in recently calved she-camels that was reflected through significant changes in steroids hormones (Drop), i.e., progesterone (P4) and estradiol (E2), the milk antioxidant biomarkers (Elevation), i.e., TAC, Se, vitamin E, and milk SCCs (Reduction). Both two therapeutic regimens had a more powerful effect that the control one.

CONCLUSION

The applied therapeutic supplements had no significant effect on clinical and hematological changes as well as calves' body weights and PWs. Body weights were significantly higher in male camel calves than those of female calves either in Cont., VitE-Se-, or Multi-.

摘要

背景

给予骆驼的所有浓缩物均以亚硒酸钠形式富硒。硒补充对哺乳期母畜健康、牛奶和硒/抗氧化状态的影响没有引起研究兴趣。

目的

本研究旨在比较产前长期注射硒-维生素 E 复合物和多种维生素对产后母骆驼临床发现、血清甾体激素、牛奶抗氧化剂、牛奶体细胞计数 (SCC) 状态、犊牛体重、胎盘重量 (PW) 和阴道冲洗分离物的影响。

方法

从产后母骆驼的三个相等组 (n = 45) 中,一组未接受治疗,作为对照组 (Cont.; n = 15)。在产前 3 个月,一组接受了维生素 E (α-生育酚) 和硒 (VitE-Se-) 的组合治疗 (n = 15),第三组接受了多种维生素 (Multi-; n = 15)。所有母骆驼均在产后第 14、21 和 28 天接受临床和实验室检测,包括牛奶总抗氧化能力 (TAC)、硒、维生素 E 和牛奶 SCC。在出生时 (第 0 天) 估计类固醇激素和犊牛和 PW。

结果

本研究报道了硒-维生素 E 组合作为产前长期注射的疗效优于多种维生素,这反映在甾体激素 (下降),即孕酮 (P4) 和雌二醇 (E2) 以及牛奶抗氧化生物标志物 (升高),即 TAC、硒、维生素 E 和牛奶 SCC 发生显著变化。两种治疗方案都比对照组效果更好。

结论

应用的治疗补充剂对临床和血液学变化以及犊牛体重和 PW 没有显著影响。在 Cont.、VitE-Se- 或 Multi-中,雄性骆驼犊牛的体重均显著高于雌性犊牛。

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