Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, P.O. Box 6622, Buraidah, 51452, Saudi Arabia.
Department of Theriogenology, Faculty of Veterinary Medicine, Assiut University, Assiut, 71526, Egypt.
Biol Trace Elem Res. 2021 Apr;199(4):1370-1376. doi: 10.1007/s12011-020-02276-8. Epub 2020 Jul 6.
This study aimed to investigate the effect of zinc (Zn), selenium (Se), and vitamin E (Vit E) administration on semen quality and fertility in male dromedary camels with impotentia generandi (IG, post-coital infertility). Factors that may affect response to treatment were investigated. Thirty-three IG-affected and five fertile camels were included. Case history was obtained, and breeding sound examination was performed. Semen was collected using electroejaculation. IG-camels were classified according to initial sperm count, body condition score, age, duration of infertility, IG-type, and testicular size. IG-camels were treated with a combination of intramuscular injections of Vit E (α-tocopherol acetate, 1 mg/kg bw) and Se (sodium selenite, 0.088 mg/kg bw) once every week for three successive weeks and by daily oral administration of 360 mg of zinc gluconate for 5 successive weeks. Semen quality was estimated before and after treatment. IG-treated camels were allowed to mate females in estrus, and conception rates were calculated. The results showed that sperm cell concentration, sperm motility, and viability significantly increased, while sperm abnormality significantly decreased after treatment (P < 0.01). Positive correlations were observed between initial sperm cell count and post-treated sperm count (P = 0.001), sperm motility (P = 0.01), and viability (P = 0.002). Other variables and their interactions did not affect response to treatment. Conception rates improved after treatment. In conclusion, Zn, Se, and Vit E administration improved semen quality and fertility in male dromedary camels with impotentia generandi. Initial sperm count can be used to predict the degree of camel response to treatment.
本研究旨在探讨补锌（Zn）、补硒（Se）和维生素 E（Vit E）对具有生殖无能（IG，交配后不孕）的雄性单峰驼精液质量和生育力的影响。研究了可能影响治疗反应的因素。共纳入 33 头 IG 受影响和 5 头生育力正常的骆驼。获取病史并进行繁殖声音检查。使用电刺激法采集精液。根据初始精子计数、体况评分、年龄、不孕持续时间、IG 类型和睾丸大小对 IG 骆驼进行分类。IG 骆驼每周接受一次肌肉注射 Vit E（α-生育酚醋酸酯，1 mg/kg bw）和 Se（亚硒酸钠，0.088 mg/kg bw），连续 3 周，每天口服 360 mg 葡萄糖酸锌，连续 5 周。在治疗前后评估精液质量。允许 IG 治疗的骆驼与发情的雌性交配，并计算受孕率。结果表明，治疗后精子细胞浓度、精子活力和活力显著增加，而精子畸形显著降低（P < 0.01）。初始精子计数与治疗后精子计数（P = 0.001）、精子活力（P = 0.01）和活力（P = 0.002）呈正相关。其他变量及其相互作用对治疗反应没有影响。治疗后受孕率提高。结论，Zn、Se 和 Vit E 给药可改善具有生殖无能的雄性单峰驼的精液质量和生育力。初始精子计数可用于预测骆驼对治疗的反应程度。
