妊娠中出现新发的颈部肌张力障碍 1 例。
A Case of New Onset Cervical Dystonia in Pregnancy.
机构信息
Department of Neurology, Beaumont hospital, Dublin, IE.
Dublin Neurological institute, Mater Misericordiae hospital, Dublin, IE.
出版信息
Tremor Other Hyperkinet Mov (N Y). 2022 Dec 23;12:33. doi: 10.5334/tohm.734. eCollection 2022.
BACKGROUND
Though uncommon, primary movement disorders can occur in pregnancy, the most common being restless legs syndrome and chorea gravidarum [1]. New onset dystonia in pregnancy has been reported four times previously with a resolution of symptoms within six months of delivery [2345]. Exacerbation of pre-existing movement disorders and the onset of de novo movement disorders during pregnancy support the hypothesis that female sex hormones play an important role in the regulation of basal ganglia circuitry.
CASE REPORT
Here we describe a case of new-onset cervical dystonia during pregnancy with persistence of symptoms after delivery.
DISCUSSION
The phenotypic overlap between this case and previously reported cases further establishes dystonia gravidarum as a distinct clinical entity.
背景
虽然不常见，但原发性运动障碍可在妊娠期间发生，最常见的是不宁腿综合征和妊娠舞蹈病[1]。此前曾有 4 次报道过妊娠期间新发的肌张力障碍，分娩后 6 个月内症状缓解[2345]。妊娠期间原有运动障碍加重和新出现运动障碍支持女性性激素在基底节回路调节中起重要作用的假说。
病例报告
此处我们描述了一例妊娠期间新发的颈肌张力障碍病例，分娩后症状持续存在。
讨论
本病例与之前报道的病例之间的表型重叠进一步确立了妊娠性肌张力障碍是一种独特的临床实体。
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