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针刺结合推拿治疗失眠的系统评价和荟萃分析。

A systematic review and meta-analysis of acupuncture combined with Tuina in the treatment of insomnia.

机构信息

Enshi Tujia and Miao Autonomous Prefecture National Hospital, Enshi City, Hubei Province, China.

The First Clinical Medical College of Nanjing University of Traditional Chinese Medicine, Enshi City, Hubei Province, China.

出版信息

Medicine (Baltimore). 2022 Dec 23;101(51):e30703. doi: 10.1097/MD.0000000000030703.

Abstract

BACKGROUND

Insomnia is a sleep disorder with insufficient sleep time or/and poor sleep quality. Relevant epidemiological studies have shown that insomnia symptoms occur in about 35% to 50% of the adult population, and it is one of the most common diseases in the elderly. Patients who often suffer from insomnia are prone to symptoms such as fatigue, weakened cognitive function, depression, and even mental illness, which bring serious physical and mental damage to individuals and a heavy economic burden to social medical care and families. Traditional Chinese medicine and modern medicine have their own advantages in the treatment of insomnia, and there is currently a lack of reports on the comparison of acupuncture combined with massage and conventional medicine.

OBJECTIVE

To evaluate the clinical efficacy of acupuncture combined with Tuina in the treatment of insomnia.

METHODS

Search for clinical randomized controlled trials (RCTs) of acupuncture combined with Tuina in the treatment of insomnia from PubMed, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wan Fang Database, and China Science and Technology Journal Database. The RevMan5.4 software was used for Meta- analysis after literature screening, data extraction and quality evaluation.

RESULTS

A total of 29 studies were included with a total of 2688 cases. Compared with drugs or acupuncture alone, acupuncture combined with Tuina has advantages in the total clinical effectiveness, as well as the Pittsburgh Sleep Quality Index (PSQI) and Statistical Self-Rating Anxiety Scale score (SAS) (OR = 3.59, 95% confidence interval [CI] [2.77, 4.66], Z = 9.62 [P < .00001]) (MD = -2.44, 95% CI [-2.93, -1.95], Z = 9.72 [P < .00001]) (MD = -8.42, 95% CI [-10.23, -6.61], Z = 9.09 [P < .00001]). There was no statistically significant difference in Statistical Self-rating Depression Scale score (SDS) (MD = -5.26, 95% CI [-11.29, 0.78], Z = 1.71 [P > .05]).

CONCLUSION

Acupuncture combined with Tuina has obvious clinical advantages in the treatment of insomnia. This result is expected to provide a reference for the clinical treatment of insomnia, but the long-term effect of clinical efficacy still needs further study.

摘要

背景

失眠是一种睡眠时间不足或/和睡眠质量差的睡眠障碍。相关的流行病学研究表明,约有 35%至 50%的成年人存在失眠症状,且它是老年人中最常见的疾病之一。经常患有失眠的患者容易出现疲劳、认知功能减弱、抑郁甚至精神疾病等症状,给个人带来严重的身心伤害,给社会医疗和家庭带来沉重的经济负担。中医和现代医学在治疗失眠方面各有优势,目前缺乏针灸结合推拿与常规医学比较的报道。

目的

评价针灸结合推拿治疗失眠的临床疗效。

方法

检索 PubMed、Cochrane 图书馆、Web of Science、中国知网、万方数据库、中国科技期刊数据库中针灸结合推拿治疗失眠的临床随机对照试验(RCT)。文献筛选、数据提取和质量评价后采用 RevMan5.4 软件进行 Meta 分析。

结果

共纳入 29 项研究,共计 2688 例患者。与药物或针灸单独治疗相比,针灸结合推拿在总临床疗效以及匹兹堡睡眠质量指数(PSQI)和统计自评焦虑量表(SAS)评分方面具有优势[比值比(OR)=3.59,95%置信区间(CI)[2.77,4.66],Z=9.62[P<0.00001])(MD=-2.44,95%CI[-2.93,-1.95],Z=9.72[P<0.00001])(MD=-8.42,95%CI[-10.23,-6.61],Z=9.09[P<0.00001])]。在统计自评抑郁量表(SDS)评分方面,差异无统计学意义(MD=-5.26,95%CI[-11.29,0.78],Z=1.71[P>0.05])。

结论

针灸结合推拿治疗失眠具有明显的临床优势。该结果有望为失眠的临床治疗提供参考,但临床疗效的长期效果仍需进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d427/9794265/f5a4ee7e5164/medi-101-e30703-g001.jpg

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