乙型肝炎病毒抗原在致倦库蚊中的持续性。

Persistence of hepatitis B viral antigens in Culex quinquefasciatus.

作者信息

Chen C C, Shou L, Hwang L L, Tang P, Tu W C, Lo H S

机构信息

Department of Parasitology and Tropical Medicine, National Defense Medical Center, Taipei, Taiwan, R.O.C.

出版信息

Southeast Asian J Trop Med Public Health. 1987 Mar;18(1):44-51.

PMID:3660067

Abstract

Culex quinquefasciatus mosquitoes were fed on or inoculated with blood or serum positive for hepatitis B viral antigens and pools of mosquitoes were tested by radioimmunoassay daily for 3 weeks after exposure to detect the viral antigens. Hepatitis B surface antigen (HBsAg) was detectable up to 3 weeks, while hepatitis B e antigen (HBeAg) persisted only for 3 days in mosquitoes after feeding on hepatitis B viral antigens-positive blood. Mosquitoes inoculated with serum were HBsAg-positive for 3 weeks and HBeAg positive for 4 days after inoculation. These results suggest that biological multiplication of hepatitis B virus did not occur in these mosquitoes. The possibility of mechanical transmission of hepatitis B antigens by mosquitoes is discussed.

摘要

用含乙型肝炎病毒抗原阳性的血液或血清喂养或接种致倦库蚊，在接触后每天通过放射免疫测定法检测蚊群3周，以检测病毒抗原。乙型肝炎表面抗原（HBsAg）在长达3周内均可检测到，而在吸食乙型肝炎病毒抗原阳性血液后，乙型肝炎e抗原（HBeAg）在蚊子体内仅持续3天。接种血清的蚊子在接种后3周内HBsAg呈阳性，HBeAg在接种后4天呈阳性。这些结果表明，乙型肝炎病毒在这些蚊子中未发生生物增殖。文中讨论了蚊子机械传播乙型肝炎抗原的可能性。