Frost S Taylor, Abdelfattah Thaer, Shah Tilak U
Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA.
Division of Gastroenterology, Hepatology, and Nutrition, Central Virginia VA Health Care System, Richmond, VA.
ACG Case Rep J. 2022 Dec 26;9(12):e00934. doi: 10.14309/crj.0000000000000934. eCollection 2022 Dec.
The typical appearance of Candida esophagitis is white plaque-like membranes within the esophagus. We describe a unique case of Candida esophagitis that presented as a bulky, malignant-appearing, positron emission tomography-computed tomography-avid mass on endoscopy. Esophageal candidiasis persisted despite a standard course of antifungal medications (fluconazole 400 mg daily for 14 days), and eradication was successful only after fluconazole 800 mg daily was administered. Malignancy was excluded based on 2 separate sessions of endoscopy with multiple biopsies and finally with endoscopic full-thickness resection assisted by preresection closure with an over-the-scope clip.
念珠菌性食管炎的典型表现是食管内出现白色斑块样膜状物。我们描述了一例独特的念珠菌性食管炎病例,在内镜检查中表现为一个体积较大、外观似恶性、正电子发射断层扫描-计算机断层扫描显示摄取增加的肿物。尽管接受了标准疗程的抗真菌药物治疗(氟康唑每日400毫克,共14天),食管念珠菌病仍持续存在,仅在每日给予800毫克氟康唑后才成功根除。基于两次独立的内镜检查及多次活检,最终通过内镜全层切除术(术前用套扎夹进行预切除闭合辅助)排除了恶性肿瘤。