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高分化十二指肠神经内分泌肿瘤所致复发性胃肠道假性梗阻

Recurrent Gastrointestinal Pseudo-obstruction Because of Well-Differentiated Duodenal Neuroendocrine Tumor.

作者信息

Sharma Ruchi, Zafar Hammad, Sherman Scott K, Niyazi Fadi

机构信息

Department of Internal Medicine, University of Iowa Hospital and Carver College of Medicine, Iowa City, IA.

Department of Surgical Oncology and Endocrine Surgery, University of Iowa Hospital and Carver College of Medicine, Iowa City, IA.

出版信息

ACG Case Rep J. 2022 Dec 26;9(12):e00910. doi: 10.14309/crj.0000000000000910. eCollection 2022 Dec.

Abstract

A 56-year-old man presented with recurrent gastrointestinal obstruction. Computed tomography showed fluid-filled, distended stomach, small intestine, and large intestine. Extensive workup including esophagogastroduodenoscopy, colonoscopy, magnetic resonance enterography, push enteroscopy, and video capsule enteroscopy showed no mechanical obstruction. Endoscopic ultrasound-guided biopsy of peripancreatic nodes detected on F-fluorodeoxyglucose positron emission tomography revealed a duodenal neuroendocrine tumor. The lesion showed intense uptake on gallium-68 DOTATOC positron emission tomography-computed tomography scan. The patient underwent surgical resection of the tumor with resolution of bowel obstruction events. He had elevated pancreatic polypeptide levels, which are known to delay gastric emptying and could explain his symptoms.

摘要

一名56岁男性因反复出现胃肠道梗阻前来就诊。计算机断层扫描显示胃、小肠和大肠充满液体且扩张。包括食管胃十二指肠镜检查、结肠镜检查、磁共振小肠造影、推进式小肠镜检查和视频胶囊内镜检查在内的全面检查未发现机械性梗阻。在F-氟脱氧葡萄糖正电子发射断层扫描中检测到的胰周淋巴结经内镜超声引导活检显示为十二指肠神经内分泌肿瘤。该病变在镓-68 DOTATOC正电子发射断层扫描-计算机断层扫描中显示摄取强烈。患者接受了肿瘤手术切除,肠梗阻症状得以缓解。他的胰多肽水平升高,已知该物质会延迟胃排空,这可以解释他的症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8954/9794233/a6833cf91b8c/ac9-9-e00910-g001.jpg

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