Schalk Gerwin, Worrell Samuel, Mivalt Filip, Belsten Alexander, Kim Inyong, Morris Jonathan M, Hermes Dora, Klassen Bryan T, Staff Nathan P, Messina Steven, Kaufmann Timothy, Rickert Jörn, Brunner Peter, Worrell Gregory A, Miller Kai J
Department of Neurosurgery, Mayo Clinic, Rochester, MN, United States.
Chen Frontier Lab for Applied Neurotechnology, Tianqiao and Chrissy Chen Institute, Shanghai, China.
Front Neurosci. 2022 Dec 19;16:932782. doi: 10.3389/fnins.2022.932782. eCollection 2022.
This article describes initial work toward an ecosystem for adaptive neuromodulation in humans by documenting the experience of implanting CorTec's BrainInterchange (BIC) device in a beagle canine and using the BCI2000 environment to interact with the BIC device. It begins with laying out the substantial opportunity presented by a useful, easy-to-use, and widely available hardware/software ecosystem in the current landscape of the field of adaptive neuromodulation, and then describes experience with implantation, software integration, and post-surgical validation of recording of brain signals and implant parameters. Initial experience suggests that the hardware capabilities of the BIC device are fully supported by BCI2000, and that the BIC/BCI2000 device can record and process brain signals during free behavior. With further development and validation, the BIC/BCI2000 ecosystem could become an important tool for research into new adaptive neuromodulation protocols in humans.
本文通过记录在一只比格犬身上植入CorTec公司的BrainInterchange（BIC）设备并使用BCI2000环境与BIC设备进行交互的经验，描述了人类适应性神经调节生态系统的初步工作。文章首先阐述了在当前适应性神经调节领域中，一个有用、易用且广泛可用的硬件/软件生态系统所带来的巨大机遇，然后描述了植入、软件集成以及术后对脑信号记录和植入参数验证的经验。初步经验表明，BCI2000完全支持BIC设备的硬件功能，并且BIC/BCI2000设备能够在自由行为期间记录和处理脑信号。随着进一步的开发和验证，BIC/BCI2000生态系统可能会成为研究人类新的适应性神经调节方案的重要工具。
