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一名儿童的指骨微地理综合征、COVID-19和抗核抗体:病例报告

Phalangeal microgeodic syndrome, COVID-19, and antinuclear antibodies in a child: A case report.

作者信息

Hanife Nura, Bessame Khaoula, Mandalia Uday Yashwant

机构信息

Department of Radiology, Watford General Hospital, Watford, Hertfordshire, United Kingdom.

出版信息

J Clin Imaging Sci. 2022 Dec 5;12:64. doi: 10.25259/JCIS_122_2022. eCollection 2022.

DOI:10.25259/JCIS_122_2022
PMID:36601602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9805605/
Abstract

Phalangeal microgeodic syndrome (PMS) is a rare rheumatological disease affecting children strongly associated with cold weather. It is considered to be benign and self-limiting, with most cases resolving in warmer months, and no studies have investigated its association to autoantibodies or viral infection. In this peculiar case, a 12-year-old child with the previous COVID-19 infection developed PMS that did not improve in the warm weather and, subsequently, Raynaud's phenomenon and facial rash. With the increasing number of new studies showing the correlation between COVID-19 and autoimmunity, this case report highlights a plausible link between COVID-19, PMS, and autoimmunity in the pediatric population that should be investigated further.

摘要

指骨微地理综合征(PMS)是一种罕见的风湿性疾病,主要影响儿童,与寒冷天气密切相关。它被认为是良性且自限性的,大多数病例在温暖月份会自行缓解,目前尚无研究探讨其与自身抗体或病毒感染的关联。在这个特殊病例中,一名曾感染过新冠病毒的12岁儿童患上了PMS,且在温暖天气下并未改善,随后还出现了雷诺现象和面部皮疹。随着越来越多的新研究表明新冠病毒与自身免疫之间存在关联,本病例报告凸显了在儿科人群中新冠病毒、PMS和自身免疫之间可能存在的联系,值得进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67dc/9805605/cc2a52341b6d/JCIS-12-64-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67dc/9805605/cc2a52341b6d/JCIS-12-64-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67dc/9805605/cc2a52341b6d/JCIS-12-64-g001.jpg

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Prevalence and titres of antinuclear antibodies in juvenile idiopathic arthritis: A systematic review and meta-analysis.幼年特发性关节炎中抗核抗体的流行率和效价:系统评价和荟萃分析。
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