Department of Biomedical Engineering, Tianjin University, 92 Weijin Road, Tianjin, 300072, China.
Institute of Wearable Technology and Bioelectronics, Qiantang Science and Technology Innovation Center, 1002 23rd Street, Hangzhou, Zhejiang, 310018, China.
Adv Healthc Mater. 2023 Apr;12(11):e2202629. doi: 10.1002/adhm.202202629. Epub 2023 Jan 16.
Advances in wearable bioelectronics interfacing directly with skin offer important tools for non-invasive measurements of physiological parameters. However, wearable monitoring devices majorly conduct static sensing to avoid signal disturbance and unreliable contact with the skin. Dynamic multiparameter sensing is challenging even with the advanced flexible skin patches. This epidermal electronics system with self-adhesive conductive electrodes to supply stable skin contact and a unique synchronous correlation peak extraction (SCPE) algorithm to minimize motion artifacts in the photoplethysmogram (PPG) signals. The skin patch system can simultaneously and precisely monitor electrocardiogram (ECG), PPG, body temperature, and acceleration on chests undergoing daily activities. The low latency between the ECG and the PPG signals enables the SCPE algorithm that leads to reduced errors in deduced heart rates and improved performance in oxygen level determination than conventional adaptive filtering and wavelet transformation approaches. Dynamic multiparameter recording over 24 h by the system can reflect the circadian patterns of the wearers with low disturbance from motion artifacts. This demonstrated system may be applied for health monitoring in large populations to alleviate pressure on medical systems and assist management of public health crisis.
可穿戴生物电子学与皮肤直接接口的进展为非侵入性测量生理参数提供了重要工具。然而,可穿戴监测设备主要进行静态感应,以避免信号干扰和与皮肤的不可靠接触。即使使用先进的柔性皮肤贴片,动态多参数感应也具有挑战性。该表皮电子系统具有自粘性导电电极,可提供稳定的皮肤接触,以及独特的同步相关峰提取 (SCPE) 算法,可最大程度地减少光体积描记图 (PPG) 信号中的运动伪影。皮肤贴片系统可以同时精确监测胸部进行日常活动时的心电图 (ECG)、PPG、体温和加速度。ECG 和 PPG 信号之间的低延迟使 SCPE 算法能够降低推导心率的误差,并提高氧水平确定的性能,优于传统的自适应滤波和小波变换方法。该系统可进行 24 小时的动态多参数记录,在低运动伪影干扰下反映佩戴者的昼夜节律模式。该演示系统可用于对大量人群进行健康监测,以减轻医疗系统的压力,并协助公共卫生危机的管理。