[与透明质酸形成复合物作为滑液中纤连蛋白异质性的原因]

[Complex-formation with hyaluronic acid as a cause of fibronectin heterogeneity in the synovial fluid].

作者信息

Abdullin A R, Litvinov R I, Zinkevich O D, Zubairov D M, Salikhov I G

出版信息

Vopr Med Khim. 1987 Jul-Aug;33(4):101-4.

Abstract

Heterogeneity of synovial fluid fibronectin was studied by means of Laurell cross-immunoelectrophoresis in patients with rheumatoid arthritis, posttraumatic synovitis and other arthropathies. Prior to hyaluronidase treatment all the synovial fluid samples exhibited the fibronectin heterogeneity, which disappeared after the action of hyaluronidase. The data obtained suggest that complexes of fibronectin and hyaluronic acid are responsible for physico-chemical heterogeneity of fibronectin in synovial fluid.

摘要

采用劳雷尔交叉免疫电泳法研究了类风湿性关节炎、创伤后滑膜炎及其他关节病患者滑液中纤连蛋白的异质性。在透明质酸酶处理之前，所有滑液样本均表现出纤连蛋白异质性，而在透明质酸酶作用后这种异质性消失。所得数据表明，纤连蛋白与透明质酸的复合物是滑液中纤连蛋白理化异质性的原因。

相似文献

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[Complex-formation with hyaluronic acid as a cause of fibronectin heterogeneity in the synovial fluid].[与透明质酸形成复合物作为滑液中纤连蛋白异质性的原因]

Vopr Med Khim. 1987 Jul-Aug;33(4):101-4.

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