Miroshnikov V M, Gabukova T V
Vopr Med Khim. 1987 Jul-Aug;33(4):73-5.
Content of hexokinase, pyruvate kinase and lactate dehydrogenase was studied in rat callus, formed in presence of commercially available preparations of placental and normal serum albumin. Total activity of all these enzymes was not similar at different stages of healing; the enzymatic activity was closely related to morpho-functional state of cellular structures in repairing zone and was dependent on their maturation. Especially pronounced changes in glycolytic enzymes activity occurred at the period of maximal proliferative activity of osteogenic cells. Placental albumin was shown to exhibit the greater stimulating effect on reparative osteogenesis as compared with the protein from blood serum.
在市售胎盘白蛋白制剂和正常血清白蛋白存在的情况下，研究了大鼠骨痂中己糖激酶、丙酮酸激酶和乳酸脱氢酶的含量。在愈合的不同阶段，所有这些酶的总活性并不相同；酶活性与修复区细胞结构的形态功能状态密切相关，并取决于它们的成熟度。糖酵解酶活性的特别显著变化发生在成骨细胞最大增殖活性期。与血清蛋白相比，胎盘白蛋白对修复性骨生成表现出更大的刺激作用。
