Grinevich Iu A, Labunets I F
Vopr Onkol. 1987;33(9):21-8.
The analysis of correlations between levels of epiphyseal, hypophyseal, adrenocortical and gonadal hormones suggested functional disorders developing in these glands to be interdependent and account for dysfunction of the thymus and immune system in patients suffering malignant melanoma. The degree of relationship between pituitary-adrenal system and thymus function disorders increased with tumor size; it was more pronounced in males. The rationale for application of pineal gland preparations in melanoma patients aimed at combatting neuroendocrine disorders is discussed.
对骨骺、垂体、肾上腺皮质和性腺激素水平之间的相关性分析表明，这些腺体中发生的功能障碍相互依存，并导致恶性黑色素瘤患者的胸腺和免疫系统功能失调。垂体 - 肾上腺系统与胸腺功能障碍之间的关系程度随肿瘤大小增加而增加；在男性中更为明显。文中讨论了在黑色素瘤患者中应用松果体制剂以对抗神经内分泌紊乱的理论依据。
