Department of Adolescent and School Health, Minhang District Center for Disease Control and Prevention, Shanghai, China.
Department of Epidemiology, Ministry of Education Key Laboratory of Public Health Safety, School of Public Health, Fudan University, Shanghai, China.
Hum Vaccin Immunother. 2022 Nov 30;18(6):2132801. doi: 10.1080/21645515.2022.2132801. Epub 2022 Oct 28.
Human papillomavirus (HPV) vaccine uptake remains low in China, especially among girls. Recently, China has initiated a pilot program on HPV immunization for girls aged 9-14 years. We conducted a cross-sectional online survey in Minhang district of Shanghai, a pilot region for the program, to investigate HPV vaccination status among mothers and their daughters 9-14. A total of 1031 parents and 1122 daughters 9-14 were included. Of them, 18.6% of mothers and 4.5% of daughters had been vaccinated with HPV vaccines or made an appointment; additionally, 62.7% and 78.4% intended to receive vaccination but did not make an appointment. Notably, 6.2% of parents did not intend to receive vaccination for themselves (or their wives) but intended to vaccinate their daughters. Moreover, we calculated parental knowledge and awareness scores toward HPV infection and vaccination. Both scores were significantly higher among the parents who had received HPV vaccination than those who intended to across mothers' vaccination status ( < .001 for knowledge and = .019 for awareness), whereas similar between the two groups across daughters' vaccination status (P = .694 and = .737). Parents believed mothers had a significantly higher susceptibility to HPV infection and lower health consequences, compared to daughters 9-12 ( = .002 and < .001) or those 13-14 (both < .001). In conclusion, HPV vaccine uptake remains a discrepancy between mothers and their daughters 9-14. However, their intents to receive HPV vaccination were both high. Parental knowledge and awareness may improve vaccination intent for daughters 9-14 in China. It warrants a certain health education toward susceptibility to HPV infection and health consequences.
人乳头瘤病毒（HPV）疫苗在中国的接种率仍然很低，尤其是在女孩中。最近，中国启动了一项针对 9-14 岁女孩的 HPV 免疫计划试点。我们在该计划的试点地区上海闵行区进行了一项横断面在线调查，以调查母亲及其 9-14 岁女儿的 HPV 疫苗接种情况。共纳入 1031 名家长和 1122 名 9-14 岁的女儿。其中，18.6%的母亲和 4.5%的女儿已经接种了 HPV 疫苗或预约接种；此外，62.7%和 78.4%的人打算接种但未预约。值得注意的是，6.2%的家长不打算为自己（或妻子）接种疫苗，但打算为女儿接种疫苗。此外，我们计算了父母对 HPV 感染和疫苗接种的知识和意识评分。在母亲接种疫苗的情况下，无论父母是否打算接种 HPV 疫苗，父母的知识和意识评分均显著高于那些打算接种的父母（知识方面 P<0.001，意识方面 P=0.019），但在女儿接种疫苗的情况下，两组之间没有差异（P=0.694 和 P=0.737）。父母认为母亲感染 HPV 的风险明显更高，且健康后果比 9-12 岁的女儿（P=0.002 和 P<0.001）或 13-14 岁的女儿（均 P<0.001）更高。结论：母亲和 9-14 岁女儿之间的 HPV 疫苗接种率仍然存在差异。然而，她们接种 HPV 疫苗的意愿都很高。父母的知识和意识可能会提高中国 9-14 岁女孩接种 HPV 疫苗的意愿。需要对 HPV 感染的易感性和健康后果进行一定的健康教育。
