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止血带使用与不使用对全膝关节置换术假体存活率、并发症和功能结果的中期影响:511 例全膝关节置换术的前瞻性队列研究。

Mid-term effect of total knee arthroplasty with and without tourniquet use on prosthesis survival, complications and functional outcome: A prospective cohort study of 511 total knee arthroplasties.

机构信息

Department of Orthopaedics, Alrijne Hospital, Simon Smitweg 1, 2353 GA Leiderdorp, the Netherlands.

Department of Orthopaedics, Alrijne Hospital, Simon Smitweg 1, 2353 GA Leiderdorp, the Netherlands.

出版信息

Knee. 2023 Mar;41:18-28. doi: 10.1016/j.knee.2022.12.012. Epub 2023 Jan 4.

DOI:10.1016/j.knee.2022.12.012
PMID:36608359
Abstract

BACKGROUND

A tourniquet is often used to create a bloodless surgical field during total knee arthroplasty (TKA). It is still debated whether tourniquet use improves durability of cemented implant fixation and thereby prosthesis survival. Some studies showed tourniquet application has a negative impact on post-operative wound healing, pain and function, whilst other publications contradict this. However, no previous studies evaluated the effect of tourniquet use on prosthesis survival and mid-term functional outcome specifically.

METHODS

In this longitudinal observational cohort study 115 patients (116 knees) undergoing TKA without tourniquet use were compared with 374 patients (395 knees) with a tourniquet. Prosthesis survival, revision risks and complications were analysed through chart review after ameanfollow-up period of5.3 years.Additionally, patient reported outcome measures regarding knee functionality and health status (PROMs; KOOS, OKS, EQ-5D, SF-12) werecollected prospectively.

RESULTS

Both groups had an equal overall re-operation rate of 4.3% and showed similar revision rates for aseptic loosening as well as for other causes. In the tourniquet group a higher complication rate (14.7% vs 10.3%) was observed. The majority was urinary retention requiring bladder catheterization. Both groups showed comparable, improved post-operative functional results compared to the pre-operative state for all PROMs atall timepoints.

CONCLUSIONS

In this study TKA without tourniquet use yielded similar mid-term results as TKA with tourniquet use with regard to prosthesis survival, reoperations, complications, knee functionality and health status.

摘要

背景

在全膝关节置换术(TKA)中,通常使用止血带来创建无血手术区域。止血带的使用是否能提高粘固植入物固定的耐久性,从而提高假体存活率,目前仍存在争议。一些研究表明止血带的应用对术后伤口愈合、疼痛和功能有负面影响,而其他一些出版物则对此提出了质疑。然而,以前没有研究专门评估止血带的使用对假体存活率和中期功能结果的影响。

方法

在这项纵向观察性队列研究中,我们比较了 115 例(116 膝)未使用止血带的 TKA 患者与 374 例(395 膝)使用止血带的患者。通过图表回顾分析了平均随访 5.3 年后的假体存活率、翻修风险和并发症。此外,前瞻性收集了患者报告的膝关节功能和健康状况(PROM;KOOS、OKS、EQ-5D、SF-12)。

结果

两组的总再手术率均为 4.3%,无菌性松动和其他原因的翻修率相似。在止血带组,观察到更高的并发症发生率(14.7% vs 10.3%)。大多数是需要导尿的尿潴留。两组在所有时间点的所有 PROM 中,与术前相比,术后的功能结果均有类似的改善。

结论

在这项研究中,不使用止血带的 TKA 在假体存活率、再手术、并发症、膝关节功能和健康状况方面与使用止血带的 TKA 具有相似的中期结果。

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