Banya Y, Okamoto T, Ujiie T, Yoo T, Noro K, Niisato S, Yokota K, Aoki H, Kubo T, Ohhori T
Department of Urology, School of Medicine, Iwate Medical University.
Hinyokika Kiyo. 1987 May;33(5):786-93.
Cefbuperazone (CBPZ) was administered to inpatients with complicated urinary tract infections (UTI) at our department. Clinical efficacy and safety were evaluated in 22 chronic cases by the criteria for evaluation of clinical of antimicrobial agents on urinary tract infection. Overall clinical efficacy was excellent in 8 cases, moderate in 9 cases and poor in 5 cases with an effectiveness rate of 77%. Twenty-four of the 34 strains isolated from the patients were eradicated and eradication rate was 71%. Neither subjective nor objective adverse reactions were observed. Abnormal changes in laboratory tests were found in 9 patients, but were probably not related to CBPZ administration. Judging from these results, CBPZ is considered to be an effective and safe antibacterial for the treatment of complicated UTI.
头孢哌酮（CBPZ）应用于我院患有复杂性尿路感染（UTI）的住院患者。依据抗菌药物治疗尿路感染的临床评价标准，对22例慢性病例的临床疗效和安全性进行了评估。总体临床疗效为8例优、9例中、5例差，有效率为77%。从患者分离出的34株菌株中，24株被清除，清除率为71%。未观察到主观或客观的不良反应。9例患者实验室检查有异常变化，但可能与使用CBPZ无关。根据这些结果，CBPZ被认为是治疗复杂性UTI的一种有效且安全的抗菌药物。
