Piras Federica, Banaj Nerisa, Ciullo Valentina, Piras Fabrizio, Ducci Giuseppe, Demaria Francesco, Vicari Stefano, Spalletta Gianfranco
Neuropsychiatry Laboratory, Department of Clinical and Behavioral Neurology, IRCCS Santa Lucia Foundation, Via Ardeatina 306, 00179 Rome, Italy.
Mental Health Department, ASL Roma 1, Piazza Santa Maria della Pietà 5-Pad. 26, 00193 Rome, Italy.
J Clin Med. 2022 Dec 28;12(1):219. doi: 10.3390/jcm12010219.
Although etiological and maintenance cognitive factors have proved effective in predicting the disease course in youths with OCD, their contribution to symptom severity and specific OCD dimensions has been scarcely examined. In a cohort of children and adolescents with OCD (N = 41; mean age = 14; age range = 10-18 yrs.), we investigated whether certain dysfunctional beliefs and cognitive traits could predict symptom severity, and whether they were differentially associated with specific symptom dimensions. We found that self-oriented and socially prescribed perfectionism and intolerance to uncertainty were associated with higher obsession severity, which was not uniquely related to any neuropsychological variable. Greater severity of obsessions and compulsions about harm due to aggression/injury/violence/natural disasters was predicted by excessive concerns with the expectations of other people. Severity in this dimension was additionally predicted by decreasing accuracy in performing a problem-solving, non-verbal reasoning task, which was also a significant predictor of severity of obsessions about symmetry and compulsions to count or order/arrange. Apart from corroborating both the belief-based and neuropsychological models of OCD, our findings substantiate for the first time the specificity of certain dysfunctional beliefs and cognitive traits in two definite symptom dimensions in youth. This bears important clinical implications for developing treatment strategies to deal with unique dysfunctional core beliefs, and possibly for preventing illness chronicity.
尽管病因学和维持性认知因素已被证明在预测患有强迫症的青少年的病程方面是有效的,但它们对症状严重程度和特定强迫症维度的影响却鲜有研究。在一组患有强迫症的儿童和青少年(N = 41;平均年龄 = 14岁;年龄范围 = 10 - 18岁)中,我们调查了某些功能失调的信念和认知特征是否能够预测症状严重程度,以及它们是否与特定症状维度存在差异关联。我们发现,自我导向型和社会规定型完美主义以及对不确定性的不耐受与更高的强迫观念严重程度相关,而这与任何神经心理学变量并无独特关联。对因攻击/伤害/暴力/自然灾害导致的伤害的强迫观念和强迫行为的更严重程度,可由对他人期望的过度担忧来预测。这一维度的严重程度还可由执行问题解决、非言语推理任务时准确性的下降来预测,而这也是对对称性的强迫观念以及计数或排序/整理的强迫行为严重程度的一个重要预测指标。除了证实强迫症基于信念和神经心理学的模型外,我们的研究结果首次证实了某些功能失调的信念和认知特征在青少年两个明确症状维度中的特异性。这对于制定应对独特功能失调核心信念的治疗策略具有重要的临床意义,并且可能对预防疾病慢性化也具有重要意义。