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[学龄儿童铅中毒:使用锌原卟啉的筛查项目结果]

[Lead poisoning in the school-aged child: results of a screening program using zinc protoporphyrin].

作者信息

Villalbí J R, Estany J, Dalmau J, Sales C, Gadea-Carrera E, Pascual-Benes A

机构信息

Servei Municipal de Sanitat, Hospitalet de Llobregat.

出版信息

An Esp Pediatr. 1987 Jul;27(1):33-6.

PMID:3662252
Abstract

The results of a zinc-protoporphyrin (ZPP) screening in 1983 among first-grade schoolchildren in Hospitalet de Llobregat (Catalonia, Spain) are presented. Tap water in this industrial city comes from the Llobregat river and is extremely hard, with an excessive level of salts. At this time, Spanish gasoline had high levels of lead. The purpose of the study was to evaluate the effect of environmental pollution on subclinical lead poisoning. These were 428 children in the study, 67% of those eligible. Causes for non participation were being absent from school on the screening day or lack of parental consent for participation in the study. Only in two children levels of ZPP above 40 theta g/100 ml were found; both cases had iron deficiency anemia with low blood lead levels. Mean ZPP levels were somewhat higher in the Collblanc district, which suffers higher air pollution from street traffic, and in children living in houses built before 1940. The relevance and implications of these findings are discussed.

摘要

本文介绍了1983年在西班牙加泰罗尼亚省略夫雷加特医院对一年级学童进行的锌原卟啉(ZPP)筛查结果。这座工业城市的自来水取自略夫雷加特河,水质极硬,盐分超标。当时,西班牙汽油中的铅含量很高。该研究的目的是评估环境污染对亚临床铅中毒的影响。研究对象为428名儿童,占符合条件者的67%。未参与的原因是筛查当天未到校或家长不同意参与研究。仅发现两名儿童的ZPP水平高于40微克/100毫升;这两个病例均为缺铁性贫血,血铅水平较低。在受街道交通空气污染较严重的科尔布兰卡区以及居住在1940年前建造房屋中的儿童中,ZPP平均水平略高。文中讨论了这些发现的相关性和意义。

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