Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Department of Biochemistry, Animal Health Research Institute, Giza, Egypt.
Nat Prod Res. 2023 Nov-Dec;37(23):4069-4079. doi: 10.1080/14786419.2022.2164577. Epub 2023 Jan 10.
(Falc.) Kasana & A.K. Pandey Family Asteraceae, formerly known as (Falc.) Lipsch contains a rich treasury of diverse bioactive compounds such as monoterpenes, sesquiterpenes, triterpenes, sterols, cardenolides, flavonoids, coumarins, lignans, phenylpropanoids and alkaloids. The sesquiterpene lactones, costunolide and dehydrocostuslactone in , possess unique promising and biological activities for the prevention and cure of diverse ailments like Parkinson's disease, oxidative stress, hyperpigmentation, ulcerative colitis, breast cancer, hepatocellular carcinoma, colon cancer, prostate cancer, ovarian cancer, leukemia, stomach cancer, prostate cancer, lung cancer, osteosarcoma, neuroblastoma, allergy, type 2 diabetes, hepatotoxicity, bronchitis, pulmonary fibrosis, thrombosis and various microbial infections. Costunolide and dehydrocostuslactone are potential drug candidates that could lead to the development of new medications for a variety of difficult-to-treat diseases.
（菊科）缬草属，曾被称为 （菊科）缬草属，含有丰富的生物活性化合物，如单萜、倍半萜、三萜、甾醇、强心苷、类黄酮、香豆素、木脂素、苯丙素和生物碱。其中，倍半萜内酯中的缬草内酯和去氢缬草内酯具有独特的预防和治疗帕金森病、氧化应激、色素沉着过度、溃疡性结肠炎、乳腺癌、肝癌、结肠癌、前列腺癌、卵巢癌、白血病、胃癌、前列腺癌、肺癌、骨肉瘤、神经母细胞瘤、过敏、2 型糖尿病、肝毒性、支气管炎、肺纤维化、血栓形成和各种微生物感染等多种疾病的潜力和生物活性。缬草内酯和去氢缬草内酯是有潜力的候选药物，可能为多种难治性疾病的治疗带来新的药物选择。
