Black W C, Goldhahn R T, Wiggins C
Department of Pathology, University of New Mexico School of Medicine, Albuquerque.
Arch Dermatol. 1987 Oct;123(10):1331-4.
The New Mexico Melanoma Registry and New Mexico Tumor Registry identified 81 cases of melanoma involving the skin and mucous membranes of Hispanics. The clinical and pathologic characteristics of these tumors were compared with those observed in whites. The frequency of melanoma in Hispanics appears to be no more than a sixth of that observed in whites. Female patients were more prevalent within the Hispanic population. The median patient age at diagnosis was similar in Hispanics and whites. A much larger proportion of melanomas in Hispanics occurred on the palms, soles, and in subungual regions. Acral lentiginous melanomas were correspondingly more frequent among Hispanics, as was mucous membrane melanoma. Melanomas arising from the palms, soles, subungual regions, and mucous membranes tended to be advanced in stage, to occur in older individuals, and to metastasize. These cases explain the generally poorer prognosis for Hispanic patients compared with whites. The epidemiology of melanoma relevant to these findings is discussed.
新墨西哥黑色素瘤登记处和新墨西哥肿瘤登记处识别出81例涉及西班牙裔皮肤和黏膜的黑色素瘤病例。将这些肿瘤的临床和病理特征与白人中观察到的特征进行了比较。西班牙裔黑色素瘤的发病率似乎不超过白人中观察到的发病率的六分之一。女性患者在西班牙裔人群中更为普遍。西班牙裔和白人患者诊断时的中位年龄相似。西班牙裔中很大一部分黑色素瘤发生在手掌、脚底和甲下区域。相应地，肢端雀斑样痣黑色素瘤在西班牙裔中更为常见，黏膜黑色素瘤也是如此。起源于手掌、脚底、甲下区域和黏膜的黑色素瘤往往分期较晚，发生在年龄较大的个体中，并且会发生转移。这些病例解释了与白人相比，西班牙裔患者总体预后较差的原因。本文讨论了与这些发现相关的黑色素瘤流行病学。
