Black W C, Wiggins C
Cancer. 1985 Jun 15;55(12):2899-902. doi: 10.1002/1097-0142(19850615)55:12<2899::aid-cncr2820551234>3.0.co;2-z.
All forms of skin cancer are uncommon among southwestern American Indians. The estimated average annual incidence of melanoma is approximately 1 per hundred thousand population or less than one tenth of that currently reported for Anglos (non-Hispanic whites) residing in the same region. This study correlates the clinical and pathologic features of melanoma in 18 American Indian patients. A marked predilection for palms, soles, and subungual locations was displayed. Additionally, three patients presented with mucous membrane primaries and two with ocular melanomas. Advanced disease stage at diagnosis was common. The protective influence of natural pigmentation in skin cancer is discussed.
在美国西南部印第安人中，各种皮肤癌都不常见。黑色素瘤的估计年平均发病率约为每十万人口1例，或低于目前居住在同一地区的盎格鲁人（非西班牙裔白人）报告发病率的十分之一。本研究对18例美国印第安黑色素瘤患者的临床和病理特征进行了相关性分析。结果显示，黑色素瘤明显好发于手掌、足底和甲下部位。此外，有3例患者以黏膜原发性黑色素瘤就诊，2例为眼黑色素瘤。确诊时疾病分期较晚很常见。本文还讨论了皮肤天然色素沉着对皮肤癌的保护作用。
