John Anil K, Varughese Betsy, Abushaikha Shaikha S, Hamdan Ahed M, Pillai Viswapriya, Ayash Ahmad M, Vincent Paul K, Sultan Khaleel, Al Ejji Khalid M, Singh Rajvir, Alabdulla Samya, Abdulmalik Mariam, Al Kaabi Saad
Gastroenterology and Hepatology, Hamad Medical Corporation, Doha, QAT.
Community Medicine, Primary Health Care Corporation, Doha, QAT.
Cureus. 2022 Dec 6;14(12):e32274. doi: 10.7759/cureus.32274. eCollection 2022 Dec.
Colorectal cancer is one of the most common cancers globally. Recent reductions in mortality rates have been primarily attributed to screening programs. The State of Qatar established a national bowel cancer screening program in 2016.
Fecal immunochemical testing (FIT) was used for average-risk individuals aged 50 to 74 years. Fecal immunochemical testing -positive participants were referred for total colonoscopy to detect polyps and cancers.
Among 32,751 FIT invitees, 11,130 took the test, and 758 (6%) of those were FIT positive. Of these, 375 (56.13%) participants underwent a colonoscopy, and polyps were detected in 198 (52.8%) and cancers in 19 (5.1%) participants. The adenoma detection rate exceeded 40%.
The high yield of polyps and cancers in the screening program justifies an active, resource-intensive, and organized bowel cancer screening effort. The high adenoma detection rate in a FIT-based program warrants recalibration of target adenoma detection rates in screening programs.
结直肠癌是全球最常见的癌症之一。近期死亡率的下降主要归功于筛查项目。卡塔尔国于2016年设立了全国性的肠癌筛查项目。
对50至74岁的平均风险个体采用粪便免疫化学检测（FIT）。粪便免疫化学检测呈阳性的参与者被转诊进行全结肠镜检查以检测息肉和癌症。
在32751名收到FIT检测邀请的人中，11130人接受了检测，其中758人（6%）FIT呈阳性。在这些人中，375名（56.13%）参与者接受了结肠镜检查，198名（52.8%）参与者检测出息肉，19名（5.1%）参与者检测出癌症。腺瘤检出率超过40%。
筛查项目中息肉和癌症的高检出率证明了积极、资源密集且有组织的肠癌筛查工作是合理的。基于FIT的项目中的高腺瘤检出率需要重新校准筛查项目中的目标腺瘤检出率。
