Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
J Med Case Rep. 2023 Jan 12;17(1):11. doi: 10.1186/s13256-022-03719-7.
Pulmonary vein thrombosis (PVT) is rarely associated with malignancies. Leiomyosarcoma, a malignant tumor originating from smooth muscles, has never been reported as the etiology of PVT.
In this case report, we described a 43-year-old Kurdish woman with a known case of leiomyosarcoma who presented with hemoptysis, dyspnea, and pleuritic chest pain. Chest computed tomography (CT) angiography revealed a thrombus in the left infero-posterior pulmonary vein. She was successfully treated with unfractionated heparin administered intravenously followed by orally administered warfarin. At the end of the article, we describe and compare other reports of malignancy-related PVT.
While malignancies are not a common cause of PVT, both primary lung tumors and metastatic cancers could be associated with PVT. Delay in diagnosis may lead to serious complications and even death. Therefore, clinicians should be aware of the possibility of the development of PVT in different malignancies for appropriate diagnosis and treatment.
肺静脉血栓形成（PVT）很少与恶性肿瘤相关。平滑肌肉瘤是一种起源于平滑肌的恶性肿瘤，从未有过作为 PVT 病因的报道。
在本病例报告中，我们描述了一位 43 岁的库尔德妇女，已知患有平滑肌肉瘤，她出现咯血、呼吸困难和胸膜炎性胸痛。胸部计算机断层扫描（CT）血管造影显示左后下肺静脉有血栓。她接受了静脉注射普通肝素和口服华法林治疗，取得了成功。在文章的最后，我们描述并比较了其他与恶性肿瘤相关的 PVT 报告。
虽然恶性肿瘤不是 PVT 的常见原因，但原发性肺肿瘤和转移性癌症都可能与 PVT 相关。诊断的延迟可能导致严重的并发症，甚至死亡。因此，临床医生应该意识到不同恶性肿瘤中 PVT 发展的可能性，以便进行适当的诊断和治疗。
