Faiek Saif, Malik Ishita, Farquhar Rhea, Lal Vikram, Bansal Aditya
Internal Medicine, AtlantiCare Regional Medical Center, Atlantic City, USA.
Internal Medicine/Pulmonary & Critical Care Medicine, AtlantiCare Regional Medical Center, Atlantic City, USA.
Cureus. 2020 May 25;12(5):e8278. doi: 10.7759/cureus.8278.
Pulmonary vein thrombosis (PVT) is a rarely encountered disease entity with varied clinical presentations. It has been reported to be associated with underlying lung malignancy in multiple case reports. Diagnosis can be challenging due to nonspecific symptoms on presentation. Herein, we report a 67-year-old male patient with a history of extensive smoking and chronic obstructive pulmonary disease (COPD) who presented with multiple hemoptysis episodes. CT scan of the chest with contrast showed multiple right lower lobe (RLL) lung masses and a thrombus in the inferior pulmonary vein. After various imaging modalities and transthoracic biopsy of the lung mass, the patient was diagnosed with pulmonary vein tumor thrombus secondary to poorly differentiated bronchogenic carcinoma with intracardiac extension. The patient was started on Eliquis for anticoagulation and is currently in the process of beginning chemo/radiation therapy for the underlying malignancy.
肺静脉血栓形成（PVT）是一种临床症状多样的罕见疾病实体。在多篇病例报告中，它被报道与潜在的肺部恶性肿瘤有关。由于发病时症状不具特异性，诊断可能具有挑战性。在此，我们报告一名67岁男性患者，有大量吸烟史和慢性阻塞性肺疾病（COPD），出现多次咯血发作。胸部增强CT扫描显示右下叶（RLL）有多个肺部肿块以及下肺静脉内有血栓。经过多种影像学检查和对肺部肿块的经胸活检，该患者被诊断为继发于低分化支气管源性癌并伴有心内延伸的肺静脉肿瘤血栓。患者开始使用阿哌沙班进行抗凝治疗，目前正在针对潜在的恶性肿瘤开始化疗/放疗。
