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慢性创伤性脑损伤患者在 COVID-19 大流行前后的抑郁、焦虑和自杀倾向:国家残疾、独立生活和康复研究创伤性脑损伤模型系统研究。

Depression, Anxiety, and Suicidality in Individuals With Chronic Traumatic Brain Injury Before and During the COVID-19 Pandemic: A National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems Study.

机构信息

Department of Physician Medicine and Rehabilitation, Indiana University School of Medicine, Indianapolis, IA; Rehabilitation Hospital of Indiana, Indianapolis, IA.

Department of Psychology, George Mason University, Fairfax, VA.

出版信息

Arch Phys Med Rehabil. 2023 Apr;104(4):619-630. doi: 10.1016/j.apmr.2022.10.017. Epub 2023 Jan 9.

DOI:10.1016/j.apmr.2022.10.017
PMID:36632965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9827731/
Abstract

OBJECTIVE

To examine the prevalence, severity, and correlates of depression, anxiety, and suicidal ideation in people with traumatic brain injury (TBI) assessed before and during the COVID-19 pandemic.

DESIGN

Retrospective cohort study using data collected through the Traumatic Brain Injury Model Systems (TBIMS) network at 1, 2, 5, 10, 15, 20, 25, or 30 years post TBI.

SETTING

United States-based TBIMS rehabilitation centers with telephone assessment of community residing participants.

PARTICIPANTS

Adults (72.4% male; mean age, 47.2 years) who enrolled in the TBIMS National Database and completed mental health questionnaires prepandemic (January 1, 2017 to February 29, 2020; n=5000) or during pandemic (April 1, 2022 to June 30, 2021; n=2009) (N=7009).

INTERVENTIONS

Not applicable.

MAIN OUTCOME MEASURES

Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 questionnaire.

RESULTS

Separate linear and logistic regressions were constructed with demographic, psychosocial, injury-related, and functional characteristics, along with a binary indicator of COVID-19 pandemic period (prepandemic vs during pandemic), as predictors of mental health outcomes. No meaningful differences in depression, anxiety, or suicidal ideation were observed before vs during the COVID-19 pandemic. Correlations between predictors and mental health outcomes were similar before and during the pandemic.

CONCLUSIONS

Contrary to our predictions, the prevalence, severity, and correlates of mental health conditions were similar before and during the COVID-19 pandemic. Results may reflect generalized resilience and are consistent with the most recent findings from the general population that indicate only small, transient increases in psychological distress associated with the pandemic. While unworsened, depression, anxiety, and suicidal ideation remain prevalent and merit focused treatment and research efforts.

摘要

目的

在 COVID-19 大流行前后评估创伤性脑损伤(TBI)患者的抑郁、焦虑和自杀意念的患病率、严重程度及其相关因素。

设计

使用通过创伤性脑损伤模型系统(TBIMS)网络收集的数据进行回顾性队列研究,该网络在 TBI 后 1、2、5、10、15、20、25 或 30 年进行评估。

地点

美国 TBIMS 康复中心,对居住在社区的参与者进行电话评估。

参与者

参加 TBIMS 国家数据库并在大流行前(2017 年 1 月 1 日至 2 月 29 日;n=5000)或大流行期间(2022 年 4 月 1 日至 2021 年 6 月 30 日;n=2009)完成心理健康问卷的成年人(72.4%为男性;平均年龄 47.2 岁)(n=7009)。

干预措施

不适用。

主要观察指标

患者健康问卷-9 项和广泛性焦虑症-7 项问卷。

结果

使用人口统计学、心理社会、损伤相关和功能特征以及 COVID-19 大流行时期(大流行前与大流行期间)的二元指标作为预测心理健康结果的因素,分别构建了线性和逻辑回归。在 COVID-19 大流行前后,未观察到抑郁、焦虑或自杀意念的明显差异。在大流行前后,预测因素与心理健康结果之间的相关性相似。

结论

与我们的预测相反,在 COVID-19 大流行前后,心理健康状况的患病率、严重程度和相关因素相似。结果可能反映了普遍的恢复力,与最近来自普通人群的发现一致,表明与大流行相关的心理困扰仅略有增加且短暂。虽然没有恶化,但抑郁、焦虑和自杀意念仍然普遍存在,值得关注治疗和研究工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbb/9827731/2b6a53c63fc9/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbb/9827731/92e299d4f2b5/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbb/9827731/2b6a53c63fc9/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbb/9827731/92e299d4f2b5/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbb/9827731/2b6a53c63fc9/gr2_lrg.jpg

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