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COVID-19 大流行对青少年、成年患者和医护人员造成的精神后遗症。

The psychiatric sequelae of the COVID-19 pandemic in adolescents, adults, and health care workers.

机构信息

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

出版信息

Depress Anxiety. 2021 Feb;38(2):233-246. doi: 10.1002/da.23120. Epub 2020 Dec 28.

Abstract

BACKGROUND

The COVID-19 pandemic is the most serious global public health crisis since the 1918 influenza pandemic. This study is the first to assess its mental health impact across the lifespan in the United States in adolescents, adults, and health care workers.

METHODS

We recruited 4909 participants through an online survey advertising on Facebook and Instagram to assess exposure to COVID-19 and psychiatric symptoms from April 27 to July 13. We also recruited through the University of Pittsburgh, University of Pittsburgh Medical Center, and other health care systems around Pittsburgh. The primary outcomes were clinically significant depression, anxiety, and posttraumatic stress disorder (PTSD) symptoms, suicidal ideation or behavior, and grief reactions since COVID-19.

RESULTS

Adolescents were significantly more likely to report moderate to severe symptoms of depression (55% vs. 29%; χ  = 122, df = 1; p < .001), anxiety (48% vs. 29%; χ  = 73; df = 1; p < .001), PTSD (45% vs. 33%; χ  = 12; df = 1; p < .001), suicidal ideation or behavior (38% vs. 16%; χ  = 117; df = 1; p < .001), and sleep problems (69% vs. 57%; χ  = 26; df = 1; p < .001) compared to adults. The rates of intense grief reactions among those who lost someone to COVID-19 was 55%. Loneliness was the most common predictor across outcomes and higher number of hours spent on social media and exposure to media about COVID-19 predicted depression symptoms and suicidal ideation or behavior in adolescents.

CONCLUSIONS

The COVID-19 pandemic is associated with increased rates of clinically significant psychiatric symptoms. Loneliness could put individuals at increased risk for the onset of psychiatric disorders.

摘要

背景

COVID-19 大流行是自 1918 年流感大流行以来最严重的全球公共卫生危机。本研究首次评估了 COVID-19 在全美青少年、成年人和医护人员全生命周期中的心理健康影响。

方法

我们通过在 Facebook 和 Instagram 上发布在线调查广告招募了 4909 名参与者,以评估他们接触 COVID-19 和从 4 月 27 日至 7 月 13 日的精神症状。我们还通过匹兹堡大学、匹兹堡大学医学中心和匹兹堡周围的其他医疗系统招募了参与者。主要结局是自 COVID-19 以来出现临床显著的抑郁、焦虑和创伤后应激障碍(PTSD)症状、自杀意念或行为以及悲伤反应。

结果

与成年人相比,青少年更有可能报告中度至重度抑郁症状(55% vs. 29%;χ²=122,df=1;p<.001)、焦虑症状(48% vs. 29%;χ²=73;df=1;p<.001)、PTSD 症状(45% vs. 33%;χ²=12;df=1;p<.001)、自杀意念或行为(38% vs. 16%;χ²=117;df=1;p<.001)和睡眠问题(69% vs. 57%;χ²=26;df=1;p<.001)。失去亲人的人中有 55%出现强烈的悲伤反应。孤独感是所有结局中最常见的预测因素,花在社交媒体上的时间和接触有关 COVID-19 的媒体时间越多,青少年的抑郁症状和自杀意念或行为的预测性就越高。

结论

COVID-19 大流行与更高的临床显著精神症状发生率相关。孤独感可能使个体面临更高的精神障碍发病风险。

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