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互联网提供的针对乳腺癌幸存者抑郁和焦虑的认知行为疗法:一项随机对照试验的结果。

Internet-delivered cognitive behavioural therapy for depression and anxiety in breast cancer survivors: Results from a randomised controlled trial.

作者信息

Akkol-Solakoglu Selin, Hevey David

机构信息

SilverCloud Science, SilverCloud Health Ltd, Dublin, Ireland.

School of Psychology, Trinity College Dublin, Dublin, Ireland.

出版信息

Psychooncology. 2023 Mar;32(3):446-456. doi: 10.1002/pon.6097. Epub 2023 Jan 30.

Abstract

OBJECTIVE

Depression and anxiety symptoms are common among breast cancer survivors. Access to evidence-based psychological therapy remains a major challenge. Despite the proven effectiveness of internet-delivered cognitive behavioural therapy (iCBT) in reducing depression and anxiety, the research with cancer survivors is still limited. This study evaluated the effectiveness of an iCBT intervention on depression and anxiety, quality of life, fear of recurrence, active and avoidant coping, and perceived social support in breast cancer survivors.

METHODS

Seventy-two participants were randomised to a 7-module guided iCBT intervention or treatment-as-usual (TAU). Depression and anxiety symptoms were measured using the Hospital Anxiety and Depression Scale total score (HADS-T). The secondary measures included the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC-QLQ), Breast Cancer Worry Scale (CWC), Brief Coping Orientation to Problems Encountered (Brief COPE), Medical Outcomes Study Social Support Survey (MOS-SSS). All were completed at baseline, post-intervention, and 2-month follow-up. Groups were compared using linear mixed models.

RESULTS

Although non-significant, iCBT group had lower HADS-T scores than TAU at post-intervention. This difference was statistically significant at 2-month follow-up (Hedge's g = -0.094). No significant group-by-time interaction effects were found for quality of life, fear of recurrence, active coping, avoidant coping, and perceived social support. The intervention adherence was acceptable; 52.8% (n = 28) completed all seven modules.

CONCLUSIONS

iCBT intervention demonstrated its preliminary effectiveness in reducing distress in breast cancer survivors.

摘要

目的

抑郁和焦虑症状在乳腺癌幸存者中很常见。获得循证心理治疗仍然是一个重大挑战。尽管基于互联网的认知行为疗法(iCBT)在减轻抑郁和焦虑方面已被证明有效,但针对癌症幸存者的研究仍然有限。本研究评估了iCBT干预对乳腺癌幸存者的抑郁、焦虑、生活质量、复发恐惧、积极和回避应对方式以及感知社会支持的有效性。

方法

72名参与者被随机分配到7个模块的指导性iCBT干预组或常规治疗(TAU)组。使用医院焦虑抑郁量表总分(HADS-T)测量抑郁和焦虑症状。次要测量指标包括欧洲癌症研究与治疗组织生活质量核心问卷(EORTC-QLQ)、乳腺癌担忧量表(CWC)、问题应对简短定向问卷(Brief COPE)、医学结局研究社会支持调查(MOS-SSS)。所有测量均在基线、干预后和2个月随访时完成。使用线性混合模型对组间进行比较。

结果

尽管不显著,但iCBT组在干预后的HADS-T得分低于TAU组。这种差异在2个月随访时具有统计学意义(Hedge's g = -0.094)。在生活质量、复发恐惧、积极应对、回避应对和感知社会支持方面,未发现显著的组×时间交互效应。干预依从性可接受;52.8%(n = 28)的参与者完成了所有七个模块。

结论

iCBT干预在减轻乳腺癌幸存者的痛苦方面显示出初步有效性。

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