The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu, China.
Anhui University of Chinese Medicine, Hefei, Anhui, China.
Integr Cancer Ther. 2024 Jan-Dec;23:15347354241293449. doi: 10.1177/15347354241293449.
To systematically review and analyze the effects of Internet-based cognitive behavioral therapy (ICBT) on physical, psychological, and daily life outcomes in patients with breast cancer.
Relevant studies were retrieved from Wanfang, CBM, CNKI, CINAHL, PsycINFO, Web of Science, The Cochrane Central Register of Controlled Trials, Embase and PubMed from inception to December 2023. Two independent authors conducted the literature search and data extraction. The Cochrane bias risk assessment tool was used to evaluate the included studies for methodological quality, and the data analysis was performed using Stata (Version 15.0).
Among 700 records, 11 randomized controlled trials were identified in this study. The meta-analysis showed statistically significant effects of ICBT on depression (standardized mean difference (SMD) = -0.38, 95% confidence interval (CI): -0.70 to -0.06, = .019) and insomnia severity (SMD = -0.71, 95% CI: -1.24 to -0.19, = .008). However, there were no statistically significant effects on anxiety, fatigue, sleep quality and quality of life.
ICBT appears to be effective for improving depression and reducing insomnia severity in patients with breast cancer, but the effects on anxiety, fatigue, sleep quality and quality of life are non-significant. This low-cost treatment needs to be further investigated. More randomized controlled trials with a larger sample size, strict study design and multiple follow-ups are required to determine the effects of ICBT on patients with breast cancer.
系统评价和分析基于互联网的认知行为疗法（ICBT）对乳腺癌患者身体、心理和日常生活结果的影响。
从万方、CBM、CNKI、CINAHL、PsycINFO、Web of Science、Cochrane 中心对照试验注册库、Embase 和 PubMed 数据库中检索从建库至 2023 年 12 月的相关研究。由 2 位作者独立进行文献检索和数据提取。采用 Cochrane 偏倚风险评估工具对纳入研究进行方法学质量评价，采用 Stata（版本 15.0）进行数据分析。
在 700 条记录中，本研究共纳入 11 项随机对照试验。Meta 分析结果显示，ICBT 对抑郁（标准化均数差（SMD）=-0.38，95%置信区间（CI）：-0.70 至-0.06，=0.019）和失眠严重程度（SMD=-0.71，95%CI：-1.24 至-0.19，=0.008）有统计学意义。但对焦虑、疲劳、睡眠质量和生活质量无统计学意义。
ICBT 似乎对改善乳腺癌患者的抑郁和降低失眠严重程度有效，但对焦虑、疲劳、睡眠质量和生活质量的影响不显著。这种低成本的治疗方法需要进一步研究。需要更多的随机对照试验，样本量更大、研究设计更严格、随访次数更多，以确定 ICBT 对乳腺癌患者的影响。
