与自闭症诊断观察量表第二版（ADOS-2）相比，儿童孤独症评定量表第二版（CARS-2）在自闭症谱系障碍诊断中的效度研究：关于临界分数的建议。
A Validation Study of the CARS-2 Compared With the ADOS-2 in the Diagnosis of Autism Spectrum Disorder: A Suggestion for Cutoff Scores.
作者信息
Ji Seong-In, Park Hyungseo, Yoon Sun Ah, Hong Soon-Beom
机构信息
Department of Psychiatry, Seoul National University Hospital, Seoul, Korea.
Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea.
出版信息
J Korean Acad Child Adolesc Psychiatry. 2023 Jan 1;34(1):45-50. doi: 10.5765/jkacap.220027.
Abstract
OBJECTIVES
This study examined the validity of the Childhood Autism Rating Scale, Second Edition (CARS-2) compared with the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) in identifying autism spectrum disorder (ASD).
METHODS
A total of 237 children were tested using both the CARS-2 and ADOS-2. We examined the correlation using Pearson's correlation analysis. In addition, we used a receiver operating characteristic graph to determine the optimal standard version of the CARS-2 (CARS2-ST) cutoff score for ASD diagnosis using the ADOS-2.
RESULTS
The concurrent validity of the CARS2-ST was demonstrated by a significant correlation with the ADOS-2 (r=0.864, p<0.001). The optimal CARS2-ST cutoff scores were 30 and 28.5 for identifying autism and autism spectrum, respectively, based on the ADOS-2.
CONCLUSION
We suggest a newly derived CARS2-ST cutoff score of 28.5 for screening ASD and providing early intervention.
摘要
目的
本研究检验了《儿童孤独症评定量表第二版》（CARS - 2）与《孤独症诊断观察量表第二版》（ADOS - 2）在识别孤独症谱系障碍（ASD）方面的有效性。
方法
共有237名儿童同时接受了CARS - 2和ADOS - 2测试。我们使用Pearson相关分析来检验相关性。此外，我们使用受试者工作特征曲线来确定基于ADOS - 2进行ASD诊断时CARS - 2（CARS2 - ST）的最佳标准版本临界值。
结果
CARS2 - ST与ADOS - 2显著相关（r = 0.864，p < 0.001），证明了其同时效度。基于ADOS - 2，识别孤独症和孤独症谱系时CARS2 - ST的最佳临界值分别为30和28.5。
结论
我们建议采用新得出的CARS2 - ST临界值28.5来筛查ASD并提供早期干预。
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本文引用的文献
1
Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2018.8 岁儿童自闭症谱系障碍的流行率和特征 - 自闭症和发育障碍监测网络，美国 11 个地点，2018 年。
MMWR Surveill Summ. 2021 Dec 3;70(11):1-16. doi: 10.15585/mmwr.ss7011a1.
2
Comparison of the Autism Diagnostic Observation Schedule and Childhood Autism Rating Scale in the Diagnosis of Autism Spectrum Disorder: A Preliminary Study.《自闭症诊断观察量表与儿童自闭症评定量表在自闭症谱系障碍诊断中的比较：一项初步研究》
Soa Chongsonyon Chongsin Uihak. 2018 Oct 1;29(4):172-177. doi: 10.5765/jkacap.180015.
3
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4
Re-adjusting the cut-off score of the Korean version of the Childhood Autism Rating Scale for high-functioning individuals with autism spectrum disorder.重新调整自闭症谱系障碍高功能个体的儿童自闭症评定量表韩文版的截断分数。
Psychiatry Clin Neurosci. 2017 Oct;71(10):725-732. doi: 10.1111/pcn.12540. Epub 2017 Jul 7.
5
The Relationship Between the Childhood Autism Rating Scale: Second Edition and Clinical Diagnosis Utilizing the DSM-IV-TR and the DSM-5.《儿童自闭症评定量表第二版与使用《精神疾病诊断与统计手册第四版，修订版》及《精神疾病诊断与统计手册第五版》进行的临床诊断之间的关系》
J Autism Dev Disord. 2016 Oct;46(10):3361-8. doi: 10.1007/s10803-016-2860-z.
6
Pervasive developmental disorder in the children of immigrant parents: comparison of different assessment instruments.移民父母子女的广泛性发育障碍：不同评估工具的比较
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7
A Comparison of the Autism Treatment Evaluation Checklist (ATEC) and the Childhood Autism Rating Scale (CARS) for the Quantitative Evaluation of Autism.用于自闭症定量评估的自闭症治疗评估清单（ATEC）与儿童自闭症评定量表（CARS）的比较
J Ment Health Res Intellect Disabil. 2013 Oct;6(4):255-267. doi: 10.1080/19315864.2012.681340.
8
Brief report: concurrent validity of autism symptom severity measures.简短报告：自闭症症状严重程度测量的同时效度
J Autism Dev Disord. 2014 Feb;44(2):466-70. doi: 10.1007/s10803-013-1879-7.
9
Prevalence of autism spectrum disorders in a total population sample.总体人群样本中自闭症谱系障碍的流行率。
Am J Psychiatry. 2011 Sep;168(9):904-12. doi: 10.1176/appi.ajp.2011.10101532. Epub 2011 May 9.
10
Comparison of scores on the Checklist for Autism Spectrum Disorder, Childhood Autism Rating Scale, and Gilliam Asperger's Disorder Scale for children with low functioning autism, high functioning autism, Asperger's disorder, ADHD, and typical development.比较低功能自闭症、高功能自闭症、艾斯伯格症、注意力缺陷多动障碍和典型发展儿童在自闭症谱系障碍检查表、儿童自闭症评定量表和吉莉安艾斯伯格症量表上的得分。
J Autism Dev Disord. 2009 Dec;39(12):1682-93. doi: 10.1007/s10803-009-0812-6. Epub 2009 Jul 16.
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