病例报告：缓解型血清阴性对称性滑膜炎伴凹陷性水肿综合征——姑息医学中一种罕见但可治疗的病症
Case Report: Syndrome of Remitting Seronegative Symmetrical Synovitis with Pitting Edema-A Rare but Treatable Condition in Palliative Medicine.
作者信息
Moore L Merkle, Brouner Jennifer M, Grigorian Nelly, Leach R J, Baumrucker Steven J
机构信息
ETSU Quillen College of Medicine, Johnson City, Tennessee, USA.
Wellstar Health System Palliative Medicine Fellowship, Marietta, Georgia, USA.
出版信息
Palliat Med Rep. 2022 Dec 26;3(1):322-325. doi: 10.1089/pmr.2021.0070. eCollection 2022.
Abstract
The syndrome of remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare diagnosis that is often missed due to lack of both definitive diagnostic criteria and awareness of the disease. This case report describes a patient with chronic lymphocytic leukemia whose diagnosis of RS3PE was possibly delayed due to concomitant treatment-related arthralgias. The pathophysiology, presentation, and treatment of RS3PE are discussed. Greater awareness of malignancy-related RS3PE is crucial from a palliative care perspective as typical opioid pain management will prove ineffective and delay appropriate treatment.
摘要
缓解型血清阴性对称性滑膜炎伴凹陷性水肿综合征（RS3PE）是一种罕见的诊断，由于缺乏明确的诊断标准和对该疾病的认识，常被漏诊。本病例报告描述了一名慢性淋巴细胞白血病患者，其RS3PE的诊断可能因同时存在的治疗相关关节痛而延迟。文中讨论了RS3PE的病理生理学、临床表现及治疗。从姑息治疗的角度来看，提高对恶性肿瘤相关RS3PE的认识至关重要，因为典型的阿片类药物疼痛管理将证明无效，并会延迟适当的治疗。
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