Mainali Naba Raj, Schmidt Torrey R, Alweis Richard, George David L
Department of Internal Medicine, Reading Health System, West Reading, PA, U.S.A.
Department of Internal Medicine, Robert Wood Johnson University Hospital, New Brunswick, NJ, U.S.A.
Am J Case Rep. 2014 Mar 21;15:119-22. doi: 10.12659/AJCR.890318. eCollection 2014.
Male, 67 FINAL DIAGNOSIS: Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome Symptoms: Bilateral wrist swelling Medication: - Clinical Procedure: - Specialty: Rheumatology.
Unusual or unexpected effect of treatment.
Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is a rare clinical entity characterized by the sudden onset of inflammatory arthritis and marked pitting edema on upper and lower extremities. RS3PE is considered a rheumatic process distinct from rheumatoid arthritis, which may occasionally represent a paraneoplastic syndrome.
Herein, we describe a rare case of RS3PE associated with insulin therapy in a patient with no evidence of underlying malignancy.
To the best of our knowledge, this is the first case report of RS3PE associated with insulin therapy. Physicians should look at the introduction of drugs as possible triggers for the development of RS3PE.
男性，67岁 最终诊断：缓解型血清阴性对称性滑膜炎伴凹陷性水肿（RS3PE）综合征 症状：双侧腕部肿胀 用药：- 临床操作：- 专科：风湿病学。
治疗的异常或意外效果。
缓解型血清阴性对称性滑膜炎伴凹陷性水肿（RS3PE）综合征是一种罕见的临床病症，其特征为炎症性关节炎突然发作以及上下肢明显的凹陷性水肿。RS3PE被认为是一种与类风湿性关节炎不同的风湿性疾病，偶尔可能代表一种副肿瘤综合征。
在此，我们描述了一例无潜在恶性肿瘤证据的患者中与胰岛素治疗相关的罕见RS3PE病例。
据我们所知，这是第一例与胰岛素治疗相关的RS3PE病例报告。医生应将药物引入视为RS3PE发生的可能触发因素。
