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印度痴呆症的流行情况:一项全国性研究的国家和邦估计数。

Prevalence of dementia in India: National and state estimates from a nationwide study.

机构信息

Center for Economic and Social Research, University of Southern California, Los Angeles, California, USA.

Department of Economics, University of Southern California, Los Angeles, California, USA.

出版信息

Alzheimers Dement. 2023 Jul;19(7):2898-2912. doi: 10.1002/alz.12928. Epub 2023 Jan 13.

DOI:10.1002/alz.12928
PMID:36637034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10338640/
Abstract

INTRODUCTION

Prior estimates of dementia prevalence in India were based on samples from selected communities, inadequately representing the national and state populations.

METHODS

From the Longitudinal Aging Study in India (LASI) we recruited a sample of adults ages 60+ and administered a rich battery of neuropsychological tests and an informant interview in 2018 through 2020. We obtained a clinical consensus rating of dementia status for a subsample (N = 2528), fitted a logistic model for dementia status on this subsample, and then imputed dementia status for all other LASI respondents aged 60+ (N = 28,949).

RESULTS

The estimated dementia prevalence for adults ages 60+ in India is 7.4%, with significant age and education gradients, sex and urban/rural differences, and cross-state variation.

DISCUSSION

An estimated 8.8 million Indians older than 60 years have dementia. The burden of dementia cases is unevenly distributed across states and subpopulations and may therefore require different levels of local planning and support.

HIGHLIGHTS

The estimated dementia prevalence for adults ages 60+ in India is 7.4%. About 8.8 million Indians older than 60 years live with dementia. Dementia is more prevalent among females than males and in rural than urban areas. Significant cross-state variation exists in dementia prevalence.

摘要

简介

先前对印度痴呆症患病率的估计是基于从选定社区抽取的样本,这些样本不能充分代表全国和各州的人口。

方法

我们从印度纵向老龄化研究(LASI)中招募了一组 60 岁以上的成年人,并在 2018 年至 2020 年期间通过丰富的神经心理测试和知情者访谈对其进行了评估。我们对一个亚组(N=2528)进行了痴呆症状态的临床共识评估,为这个亚组拟合了一个痴呆症状态的逻辑模型,然后为所有其他 LASI 60 岁以上的受访者(N=28949)推断了痴呆症状态。

结果

印度 60 岁以上成年人的痴呆症患病率估计为 7.4%,具有显著的年龄和教育梯度、性别和城乡差异以及跨州差异。

讨论

估计有 880 万印度 60 岁以上的成年人患有痴呆症。痴呆症病例的负担在各州和亚人群中分布不均,因此可能需要不同程度的地方规划和支持。

亮点

印度 60 岁以上成年人的痴呆症患病率估计为 7.4%。约有 880 万 60 岁以上的印度人患有痴呆症。女性比男性、农村比城市地区更易患痴呆症。痴呆症的患病率在各州之间存在显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9775/10338640/4c671de44783/nihms-1878818-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9775/10338640/c30d13e6b71e/nihms-1878818-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9775/10338640/5785b53bccfa/nihms-1878818-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9775/10338640/4c671de44783/nihms-1878818-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9775/10338640/c30d13e6b71e/nihms-1878818-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9775/10338640/5785b53bccfa/nihms-1878818-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9775/10338640/4c671de44783/nihms-1878818-f0003.jpg

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