利用微计算机断层扫描和纳米压痕技术研究犬牙本质的矿物质密度和弹性模量的相关性。
Correlation of mineral density and elastic modulus of dog dentin using μ-CT and nanoindentation.
机构信息
Department of Surgical Sciences, University of Wisconsin-Madison, School of Veterinary Medicine, Madison, WI, USA.
Carbone Cancer Center, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, WI, USA.
出版信息
J Biomech. 2023 Jan;147:111434. doi: 10.1016/j.jbiomech.2023.111434. Epub 2023 Jan 7.
This study sought to 1) investigate the spatial distribution of mineral density of dog dentin using µ-CT and 2) characterize the relationship between the elastic modulus and mineral density of dog dentin using nanoindentation and µ-CT. Maxillary canine teeth of 10 mature dogs were scanned with a µ-CT then sectioned in the transverse and vertical planes and tested using nanoindentation. Spatial distribution of mineral density and elastic modulus was quantified. Results demonstrated significant spatial variation in mineral density and elastic modulus. Mineral density and elastic modulus generally increased from the dentin-pulp interface to the dentino-enamel junction and from the crown base to the crown tip. Significant site dependent correlations between mineral density and elastic modulus were determined (0.021 > R > 0.408). The results of this study suggest that while mineral density is a mediator of elastic modulus, other mediators such as collagen content may contribute to the mechanical behavior of dog dentin.
本研究旨在
1）利用μ-CT 研究狗牙本质的矿物质密度的空间分布；2）利用纳米压痕和 μ-CT 描述狗牙本质的弹性模量与矿物质密度之间的关系。对 10 颗成熟犬的上颌尖牙进行μ-CT 扫描，然后沿横向和纵向平面进行切片，并进行纳米压痕测试。对矿物质密度和弹性模量的空间分布进行量化。结果表明，矿物质密度和弹性模量具有显著的空间变化。矿物质密度和弹性模量通常从牙本质-牙髓界面到牙本质-釉质交界处，以及从冠基部到冠顶逐渐增加。确定了矿物质密度和弹性模量之间具有显著的位置依赖性相关性（0.021＞R＞0.408）。本研究的结果表明，虽然矿物质密度是弹性模量的介质，但其他介质如胶原含量可能会影响狗牙本质的力学性能。
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