序贯器官衰竭评估 (SOFA) 评分：是否到了更新的时候？
The Sequential Organ Failure Assessment (SOFA) Score: has the time come for an update?
机构信息
Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Faculdade de Ciências Médicas de Lisboa, Nova Médical School, Lisbon, Portugal.
Faculdade de Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal.
出版信息
Crit Care. 2023 Jan 13;27(1):15. doi: 10.1186/s13054-022-04290-9.
Abstract
The Sequential Organ Failure Assessment (SOFA) score was developed more than 25 years ago to provide a simple method of assessing and monitoring organ dysfunction in critically ill patients. Changes in clinical practice over the last few decades, with new interventions and a greater focus on non-invasive monitoring systems, mean it is time to update the SOFA score. As a first step in this process, we propose some possible new variables that could be included in a SOFA 2.0. By so doing, we hope to stimulate debate and discussion to move toward a new, properly validated score that will be fit for modern practice.
摘要
序贯器官衰竭评估（SOFA）评分系统于 25 年前开发，旨在为危重症患者的器官功能障碍评估和监测提供一种简单的方法。过去几十年间，临床实践发生了变化，新的干预措施和对非侵入性监测系统的关注增加，这意味着现在是时候更新 SOFA 评分了。作为这一过程的第一步，我们提出了一些可能包含在 SOFA 2.0 中的新变量。通过这样做，我们希望能够激发讨论和辩论，以制定一个新的、经过适当验证的评分系统，使其适用于现代临床实践。
相似文献
1
The Sequential Organ Failure Assessment (SOFA) Score: has the time come for an update?
Crit Care. 2023 Jan 13;27(1):15. doi: 10.1186/s13054-022-04290-9.
2
Adaptation and Validation of a Pediatric Sequential Organ Failure Assessment Score and Evaluation of the Sepsis-3 Definitions in Critically Ill Children.
JAMA Pediatr. 2017 Oct 2;171(10):e172352. doi: 10.1001/jamapediatrics.2017.2352.
3
Acute kidney injury enhances outcome prediction ability of sequential organ failure assessment score in critically ill patients.
PLoS One. 2014 Oct 3;9(10):e109649. doi: 10.1371/journal.pone.0109649. eCollection 2014.
4
Utility of SOFA and Δ-SOFA scores for predicting outcome in critically ill patients from the emergency department.
Eur J Emerg Med. 2018 Dec;25(6):387-393. doi: 10.1097/MEJ.0000000000000472.
5
Quick chronic liver failure-sequential organ failure assessment: an easy-to-use scoring model for predicting mortality risk in critically ill cirrhosis patients.
Eur J Gastroenterol Hepatol. 2017 Jun;29(6):698-705. doi: 10.1097/MEG.0000000000000856.
6
Scoring systems for 6-month mortality in critically ill cirrhotic patients: a prospective analysis of chronic liver failure - sequential organ failure assessment score (CLIF-SOFA).
Aliment Pharmacol Ther. 2014 Nov;40(9):1056-65. doi: 10.1111/apt.12953. Epub 2014 Sep 11.
7
Glasgow Coma Scale score dominates the association between admission Sequential Organ Failure Assessment score and 30-day mortality in a mixed intensive care unit population.
J Crit Care. 2014 Oct;29(5):780-5. doi: 10.1016/j.jcrc.2014.05.009. Epub 2014 May 28.
8
Multiple organ system failure in critically ill cirrhotic patients. A comparison of two multiple organ dysfunction/failure scoring systems.
Digestion. 2004;69(3):190-200. doi: 10.1159/000078789. Epub 2004 Jun 1.
9
Predictive Validity of the Sequential Organ Failure Assessment Score versus Claims-based Scores among Critically Ill Patients.
Ann Am Thorac Soc. 2022 Jun;19(6):1072-1076. doi: 10.1513/AnnalsATS.202111-1251RL.
10
Advances in management and prognostication in critically ill cirrhotic patients.
Curr Opin Crit Care. 2014 Apr;20(2):210-7. doi: 10.1097/MCC.0000000000000067.
引用本文的文献
1
Enhancing prognostic accuracy in sepsis: a modified SOFA score incorporating lymphocyte count as an immune function marker.
Front Cell Infect Microbiol. 2025 Jul 31;15:1593589. doi: 10.3389/fcimb.2025.1593589. eCollection 2025.
2
Evaluating the diagnostic performance of adult sepsis event criteria in the emergency department: impact of including isolated serum lactate elevations.
J Intensive Care. 2025 Aug 15;13(1):44. doi: 10.1186/s40560-025-00815-w.
3
Exploring pharmacological strategies in the management of ARDS: Efficacy, limitations, and future directions.
J Crit Care Med (Targu Mures). 2025 Jul 31;11(3):208-220. doi: 10.2478/jccm-2025-0030. eCollection 2025 Jul.
4
Reevaluating anticoagulation therapy for sepsis-associated disseminated intravascular coagulation based on endothelial glycocalyx shedding quantification: a single-center, retrospective, observational pilot study.
Front Med (Lausanne). 2025 Jul 16;12:1566753. doi: 10.3389/fmed.2025.1566753. eCollection 2025.
5
Association Between ST-Segment Deviation in Electrocardiography and 30-Day Mortality in Non-Cardiac Critically Ill Patients: A Retrospective Single-Center Study.
J Clin Med. 2025 Jul 10;14(14):4911. doi: 10.3390/jcm14144911.
6
The Prognostic Role of Pitt Bacteremia Score in Patients With Nonbacteremic Infections.
Can J Infect Dis Med Microbiol. 2025 Jul 15;2025:6780766. doi: 10.1155/cjid/6780766. eCollection 2025.
7
Effectiveness of predictive scoring systems in predicting mortality in relation to baseline kidney function in adult intensive care unit patients: a systematic review protocol.
BMJ Open. 2025 Jul 17;15(7):e098192. doi: 10.1136/bmjopen-2024-098192.
8
Does the change in Liver Frailty Index over the first week of hospitalisation predict mortality in patients with acute-on-chronic liver failure? A prospective cohort study from a Slovak liver centre.
BMJ Open. 2025 May 28;15(5):e100171. doi: 10.1136/bmjopen-2025-100171.
9
A machine learning and centrifugal microfluidics platform for bedside prediction of sepsis.
Nat Commun. 2025 May 27;16(1):4442. doi: 10.1038/s41467-025-59227-x.
10
Association between advanced lung cancer inflammation index and mortality in critically ill septic patients: analysis of the MIMIC-IV database.
BMC Infect Dis. 2025 May 24;25(1):747. doi: 10.1186/s12879-025-11116-w.
本文引用的文献
1
The Use of Metaraminol as a Vasopressor in Critically Unwell Patients: A Narrative Review and a Survey of UK Practice.
J Crit Care Med (Targu Mures). 2022 Aug 12;8(3):193-203. doi: 10.2478/jccm-2022-0017. eCollection 2022 Jul.
2
Pulse oximetry for the diagnosis and management of acute respiratory distress syndrome.
Lancet Respir Med. 2022 Nov;10(11):1086-1098. doi: 10.1016/S2213-2600(22)00058-3. Epub 2022 Aug 29.
3
ARDS Clinical Practice Guideline 2021.
J Intensive Care. 2022 Jul 8;10(1):32. doi: 10.1186/s40560-022-00615-6.
4
High-Flow Oxygen Therapy for Severe Hypoxemia: Moving toward a More Inclusive Definition of Acute Respiratory Distress Syndrome.
Am J Respir Crit Care Med. 2022 Aug 15;206(4):514-515. doi: 10.1164/rccm.202201-0185LE.
5
Analysis of Discrepancies Between Pulse Oximetry and Arterial Oxygen Saturation Measurements by Race and Ethnicity and Association With Organ Dysfunction and Mortality.
JAMA Netw Open. 2021 Nov 1;4(11):e2131674. doi: 10.1001/jamanetworkopen.2021.31674.
6
Missing data methods for intensive care unit SOFA scores in electronic health records studies: results from a Monte Carlo simulation.
J Comp Eff Res. 2022 Jan;11(1):47-56. doi: 10.2217/cer-2021-0079. Epub 2021 Nov 2.
7
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.
Intensive Care Med. 2021 Nov;47(11):1181-1247. doi: 10.1007/s00134-021-06506-y. Epub 2021 Oct 2.
8
ELSO Interim Guidelines for Venoarterial Extracorporeal Membrane Oxygenation in Adult Cardiac Patients.
ASAIO J. 2021 Aug 1;67(8):827-844. doi: 10.1097/MAT.0000000000001510.
9
Critical carE Database for Advanced Research (CEDAR): An automated method to support intensive care units with electronic health record data.
J Biomed Inform. 2021 Jun;118:103789. doi: 10.1016/j.jbi.2021.103789. Epub 2021 Apr 14.
10
Blood lactate levels in sepsis: in 8 questions.
Curr Opin Crit Care. 2021 Jun 1;27(3):298-302. doi: 10.1097/MCC.0000000000000824.
Zotero 插件