伽马辐射对埃及伊蚊（双翅目：蚊科）传播寨卡病毒的媒介能力的影响。

Effects of gamma radiation on the vector competence of Aedes aegypti (diptera: Culicidae) to transmit Zika virus.

作者信息

da Silva Edvane Borges, de Mendonça Carlos Messias, Guedes Duschinka Ribeiro Duarte, Paiva Marcelo Henrique Santos, Mendonça Jaziela de Arruda, Dias Elisângela Santos Ferreira, Florêncio Sloana Giesta Lemos, Amaral Ademir, Netto André Maciel, Lopes Constância Flávia Junqueira Ayres, de Melo-Santos Maria Alice Varjal

机构信息

Centro Acadêmico de Vitória (CAV), Universidade Federal de Pernambuco (UFPE), Vitoria de Santo Antão, Pernambuco, Brazil; Group of Studies in Radioprotection and Radioecology (GERAR), Department of Nuclear Energy (DEN), Postgraduate Programme in Energy and Nuclear Technologies (PROTEN), Universidade Federal de Pernambuco (UFPE), Recife, Pernambuco, Brazil.

Centro Acadêmico de Vitória (CAV), Universidade Federal de Pernambuco (UFPE), Vitoria de Santo Antão, Pernambuco, Brazil.

出版信息

Acta Trop. 2023 Mar;239:106831. doi: 10.1016/j.actatropica.2023.106831. Epub 2023 Jan 11.

DOI:10.1016/j.actatropica.2023.106831

PMID:36640923

Abstract

One of the limitations of the Sterile Insect Technique (SIT), conventionally performed by ionizing radiation, regards separating males from females, which is not 100% effective. Some irradiated females may be released together with males in the field at SIT. The present study aimed to evaluate the influence of ionizing radiation on the ability of Aedes aegypti mosquitoes to transmit the Zika virus after exposing female pupae to a 40 Gy of gamma radiation. The results suggest that the genetic damage induced by exposure of females to this dose level promotes their total sterility, but it does not influence their vector competence. However, our data point out that ionizing radiation may decrease the proportion of infective mosquitoes.

摘要

传统上通过电离辐射实施的绝育昆虫技术（SIT）存在一个局限性，即区分雄蚊和雌蚊，这并非100%有效。在SIT中，一些经辐射的雌蚊可能会与雄蚊一起在野外释放。本研究旨在评估在将雌性蛹暴露于40戈瑞的γ辐射后，电离辐射对埃及伊蚊传播寨卡病毒能力的影响。结果表明，雌性暴露于该剂量水平的辐射所诱导的基因损伤会导致其完全不育，但并不影响它们的媒介能力。然而，我们的数据指出，电离辐射可能会降低感染性蚊子的比例。