Medical University of South Carolina, Charleston, South Carolina.
Medical University of South Carolina, Charleston, South Carolina.
J AAPOS. 2023 Feb;27(1):24.e1-24.e7. doi: 10.1016/j.jaapos.2022.11.019. Epub 2023 Jan 13.
To evaluate the Spot Vision Screener according to updated 2021 AAPOS Vision Screening Committee guidelines for instrument-based pediatric vision screen validation.
As part of an IRB-approved ongoing prospective study, children were screened with the Spot prior to a complete examination.
Spot screening was successful in 1,036 of 1,090 children (95%). Forty-eight percent of participants were referred for further screening using the Spot manufacturer guidelines, and 40% of all children were found to have a 2021 amblyopia risk factor or visually significant refractive error by gold standard examination. The Spot recommendation compared reasonably well to the 2021 criteria, with an overall sensitivity of 0.88 and a specificity of 0.78. Applying updated guidelines to the Spot for hyperopia, anisometropia, and astigmatism yielded moderate-to-poor sensitivity (0.27-0.77) but excellent specificity (>0.9). The area under the curve of the receiver operating characteristic analysis demonstrates overall good prediction performance for the Spot for each diagnosis-myopia, hyperopia, astigmatism, anisometropia (range, 0.87-0.97). Results of our study suggest increasing the instrument referral criterion for astigmatism from 1.5 D (manufacturer thresholds of the screener used in this study) to 2 D in older children. Decreasing the anisometropia cut-off from 1 D to 0.75 D would improve sensitivity from 0.59 to >0.8.
In our study population, the overall predictive ability of the Spot is good, with a sensitivity of 0.88 and a specificity of 0.78. We recommend specific device refractive referral criteria to maximize screening effectiveness using the updated AAPOS guidelines.
根据 2021 年 AAPOS 视觉筛查委员会更新的仪器验证儿童视觉筛查指南评估 Spot Vision Screener。
作为一项经机构审查委员会批准的正在进行的前瞻性研究的一部分,在对儿童进行全面检查之前,使用 Spot 进行筛查。
Spot 筛查在 1090 名儿童中有 1036 名(95%)成功。根据 Spot 制造商的指南,48%的参与者被推荐进一步筛查,40%的儿童通过金标准检查发现患有 2021 年弱视风险因素或明显的屈光不正。Spot 的建议与 2021 年的标准相比相当合理,总灵敏度为 0.88,特异性为 0.78。根据更新的标准,将远视、屈光参差和散光应用于 Spot,敏感性为中度至较差(0.27-0.77),但特异性极好(>0.9)。受试者工作特征曲线的曲线下面积表明 Spot 对每种诊断(近视、远视、散光、屈光参差)的整体预测性能均良好(范围,0.87-0.97)。我们的研究结果表明,在年龄较大的儿童中,将散光的仪器转诊标准从 1.5 D(本研究中使用的筛查仪制造商阈值)提高到 2 D。将屈光参差的截止值从 1 D 降低到 0.75 D,可将敏感性从 0.59 提高到>0.8。
在我们的研究人群中,Spot 的总体预测能力良好,灵敏度为 0.88,特异性为 0.78。我们建议使用更新的 AAPOS 指南,采用特定的设备屈光转诊标准,以最大程度地提高筛查效果。