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绝经后女性骨质疏松症治疗选择的最新知识

Up-to-Date Knowledge on Osteoporosis Treatment Selection in Postmenopausal Women.

作者信息

Jeong Hye Gyeong, Kim Min Kyung, Lim Hee Jeung, Kim Seul Ki

机构信息

Department of Obstetrics and Gynecology, Korea University Anam Hospital, Seoul, Korea.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.

出版信息

J Menopausal Med. 2022 Dec;28(3):85-91. doi: 10.6118/jmm.22007.

DOI:10.6118/jmm.22007
PMID:36647271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9843036/
Abstract

The concept of a super-aged society has led to a steady increase in the average lifespan and hence, interest in a healthy life has increased. Aging is a major risk factor for many diseases, including osteoporosis. Osteoporotic fractures have a significant impact on the quality of life of the elderly and hence, it is pivotal to provide effective treatment of osteoporosis after menopause. Osteoporosis requires proper management and the treatment must be centered on long-term goals. New drugs with diverse mechanisms have been developed for treating osteoporosis. Current management of osteoporosis generally focuses on the importance of risk-based strategies to maximize the effectiveness of existing treatments and mitigate potential negative side-effects. Additionally, there is a need for sequential treatment of osteoporosis in the future. This review discusses the dynamic strategies for osteoporosis treatment and the importance of long-term management in postmenopausal women.

摘要

超老龄化社会的概念导致平均寿命稳步增长,因此,人们对健康生活的兴趣也有所增加。衰老是包括骨质疏松症在内的许多疾病的主要危险因素。骨质疏松性骨折对老年人的生活质量有重大影响,因此,在绝经后提供有效的骨质疏松症治疗至关重要。骨质疏松症需要适当的管理,治疗必须以长期目标为中心。已经开发出具有多种作用机制的新药来治疗骨质疏松症。目前骨质疏松症的管理通常侧重于基于风险的策略的重要性,以最大限度地提高现有治疗的有效性并减轻潜在的负面副作用。此外,未来还需要对骨质疏松症进行序贯治疗。本综述讨论了绝经后妇女骨质疏松症治疗的动态策略以及长期管理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9dc/9843036/666f831a7bc7/jmm-28-85-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9dc/9843036/690537a8d163/jmm-28-85-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9dc/9843036/666f831a7bc7/jmm-28-85-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9dc/9843036/690537a8d163/jmm-28-85-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9dc/9843036/666f831a7bc7/jmm-28-85-g002.jpg

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