[口腔微生物群与全身性疾病]
[Oral Microbiome and Systemic Diseases].
作者信息
Zhou Lu-Jun, Chen Bo-Yan, Li Yu-Lin, Duan Sheng-Zhong
机构信息
Laboratory of Oral Microbiota and Systemic Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases.
Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai 200011, China.
出版信息
Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 Jan;54(1):1-6. doi: 10.12182/20230160504.
As one of the most diverse microbial communities within the human body, the oral microbiome is an important component that contributes to the maintenance of human health. The microbial composition of different sites in the oral cavity varies significantly and a dynamic equilibrium is maintained through communications with the environment and oral and distal organs of the host. It has been reported that there is significant correlation between dysbiotic oral microbiome and the occurrence or progression of a variety of systemic diseases. In this review, we summarized recent advances in research on the relationship between oral microbiome and systemic health, focusing on the interaction and pathological mechanisms between oral microbiome and systemic health and hoping to provide new avenues for the early prevention and clinical diagnosis and treatment of systemic diseases.
作为人体内最多样化的微生物群落之一，口腔微生物群是有助于维持人类健康的重要组成部分。口腔不同部位的微生物组成差异显著，通过与环境以及宿主的口腔和远端器官进行交流来维持动态平衡。据报道，口腔微生物群失调与多种全身性疾病的发生或进展之间存在显著相关性。在本综述中，我们总结了口腔微生物群与全身健康关系的最新研究进展，重点关注口腔微生物群与全身健康之间的相互作用和病理机制，希望为全身性疾病的早期预防以及临床诊断和治疗提供新途径。
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