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评估猫下尿路疾病:肾脏多普勒超声检查。

Evaluating feline lower urinary tract disease: Doppler ultrasound of the kidneys.

机构信息

Department of Veterinary Medicine, Federal University of Viçosa, Viçosa, Brazil.

出版信息

J Feline Med Surg. 2023 Jan;25(1):1098612X221145477. doi: 10.1177/1098612X221145477.

DOI:10.1177/1098612X221145477
PMID:36649073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10812048/
Abstract

OBJECTIVES

Ultrasonography is used in the evaluation of urinary disorders, and the resistivity index (RI) and pulsatility index (PI) have been successfully used to detect early hemodynamic changes in the course of kidney diseases in humans and dogs. The aim of this study was to investigate RI and PI in cats with feline lower urinary tract disease (FLUTD).

METHODS

Twenty-nine client-owned cats were selected and divided into a control group (CG; n = 10), a group of animals with obstructive FLUTD (OG; n = 11) and non-obstructive FLUTD (nOG; n = 8). Clinical, laboratory and ultrasound evaluations were performed in all cats.

RESULTS

RI and PI values for cats in the CG were below the upper limit of normal suggested in other studies, while cats with FLUTD showed significantly higher values in the assessment of RI ( = 0.027 and  = 0.034, respectively) and PI ( = 0.044 and  = 0.048, respectively) of the right and left kidneys.

CONCLUSIONS AND RELEVANCE

Alteration in renal blood flow was observed in cats with lower urinary tract disorders, even in the nOG group. To the best of our knowledge, this is the first report of renal blood flow changes related to non-obstructive FLUTD.

摘要

目的

超声检查用于评估泌尿系统疾病,阻力指数(RI)和搏动指数(PI)已成功用于检测人类和犬类肾脏疾病过程中的早期血液动力学变化。本研究旨在探讨下尿路疾病(FLUTD)猫的 RI 和 PI。

方法

选择 29 只患猫并将其分为对照组(CG;n=10)、梗阻性 FLUTD 组(OG;n=11)和非梗阻性 FLUTD 组(nOG;n=8)。对所有猫进行临床、实验室和超声评估。

结果

CG 猫的 RI 和 PI 值低于其他研究中建议的正常上限,而 FLUTD 猫的 RI( = 0.027 和  = 0.034)和 PI( = 0.044 和  = 0.048)的左右肾脏评估值明显更高。

结论和相关性

下尿路疾病猫的肾血流发生改变,即使在 nOG 组也是如此。据我们所知,这是首次报道与非梗阻性 FLUTD 相关的肾血流变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9a5/10812048/d9df01e0e18f/10.1177_1098612X221145477-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9a5/10812048/c18eb97e513e/10.1177_1098612X221145477-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9a5/10812048/d9df01e0e18f/10.1177_1098612X221145477-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9a5/10812048/c18eb97e513e/10.1177_1098612X221145477-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9a5/10812048/d9df01e0e18f/10.1177_1098612X221145477-fig2.jpg

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2
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J Equine Vet Sci. 2021 Aug;103:103662. doi: 10.1016/j.jevs.2021.103662. Epub 2021 May 24.
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Feline abdominal ultrasonography: what's normal? what's abnormal? The kidneys and perinephric space.
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J Feline Med Surg. 2020 May;22(5):409-427. doi: 10.1177/1098612X20917598.
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Roles of Inflammasomes in Inflammatory Kidney Diseases.炎性小体在炎症性肾脏疾病中的作用。
Mediators Inflamm. 2019 Jul 21;2019:2923072. doi: 10.1155/2019/2923072. eCollection 2019.
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Chronic Lower Urinary Tract Signs in Cats: Current Understanding of Pathophysiology and Management.猫慢性下尿路症状:当前对病理生理学及管理的认识
Vet Clin North Am Small Anim Pract. 2019 Mar;49(2):187-209. doi: 10.1016/j.cvsm.2018.11.001.
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Ther Adv Urol. 2019 Jan 8;11:1756287218818030. doi: 10.1177/1756287218818030. eCollection 2019 Jan-Dec.
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J Nephrol. 2019 Aug;32(4):527-538. doi: 10.1007/s40620-018-00567-x. Epub 2018 Dec 11.
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