Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea.
Department of Periodontology, Seoul National University Dental Hospital, Seoul, Korea.
Sci Rep. 2023 Jan 17;13(1):862. doi: 10.1038/s41598-023-27712-2.
Recently, double-root implants have been investigated using 3D-printed technology. Here, we investigated damping capacity, microcomputed tomographic (micro-CT) and histological analyses of double-root 3D-printed implants compared with single-root 3D printed implants. Single- and double-root 3D-printed implants were fabricated and placed at both sides of mandibular third and fourth premolars in four beagle dogs. The damping capacity was measured, and periapical X-rays were taken every 2 weeks for 12 weeks. The bone volume/tissue volume (BV/TV) and bone mineral density (BMD) around the implants were measured with micro-CT. Bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO) were measured in histological samples. The implant stability values between the groups were not significantly different, except at 4 and 12 weeks. The marginal bone changes were similar at the mesial and distal areas between the groups. The BV/TV and BMD values of the double-root 3D-printed implants showed no statistical difference through micro-CT analysis, but the double-root 3D-printed implants showed lower BIC and BAFO values through histomorphometric analysis compared to the single-root 3D-printed implants. Compared to single-root implants, 3D-printed double-root implants demonstrated comparable stability and bone remodeling around the fixtures, but the statistically significant bone loss in the furcation area remains problematic.
最近，利用 3D 打印技术研究了双根种植体。在这里，我们研究了双根 3D 打印种植体与单根 3D 打印种植体相比的阻尼能力、微计算机断层扫描（micro-CT）和组织学分析。在四只比格犬的下颌第三和第四前磨牙的两侧分别制作和放置单根和双根 3D 打印种植体。测量了阻尼能力，并在 12 周内每 2 周拍摄根尖 X 线片。使用 micro-CT 测量种植体周围的骨体积/组织体积（BV/TV）和骨矿物质密度（BMD）。在组织学样本中测量了骨-种植体接触（BIC）和骨面积分数占有率（BAFO）。除了在 4 周和 12 周外，两组之间的种植体稳定性值没有显著差异。组间近远中骨边缘变化相似。通过 micro-CT 分析，双根 3D 打印种植体的 BV/TV 和 BMD 值没有统计学差异，但与单根 3D 打印种植体相比，双根 3D 打印种植体的 BIC 和 BAFO 值较低。与单根种植体相比，3D 打印双根种植体在固定装置周围显示出可比较的稳定性和骨重塑，但分叉区的统计学显著骨丢失仍然是一个问题。
