Li Ling, Lee Jungwon, Amara Heithem Ben, Lee Jun-Beom, Lee Ki-Sun, Shin Sang-Wan, Lee Yong-Moo, Kim Byoungkook, Kim Pangyu, Koo Ki-Tae
Department of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul 03080, Korea.
One-Stop Specialty Center, Seoul National University Dental Hospital & Department of Periodontology, School of Dentistry, Seoul National University, Seoul 03080, Korea.
Materials (Basel). 2020 Oct 28;13(21):4815. doi: 10.3390/ma13214815.
This study aimed to compare bone healing and implant stability for three types of dental implants: a threaded implant, a three-dimensional (3D)-printed implant without spikes, and a 3D-printed implant with spikes. In four beagle dogs, left and right mandibular premolars (2nd, 3rd, and 4th) and 1st molars were removed. Twelve weeks later, three types of titanium implants (threaded implant, 3D-printed implant without spikes, and 3D-printed implant with spikes) were randomly inserted into the edentulous ridges of each dog. Implant stability measurements and radiographic recordings were taken every two weeks following implant placement. Twelve weeks after implant surgery, the dogs were sacrificed and bone-to-implant contact (BIC) and bone area fraction occupied (BAFO) were compared between groups. At implant surgery, the primary stability was lower for the 3D-printed implant with spikes (74.05 ± 5.61) than for the threaded implant (83.71 ± 2.90) ( = 0.005). Afterwards, no significant difference in implants' stability was observed between groups up to post-surgery week 12. Histomorphometrical analysis did not reveal a significant difference between the three implants for BIC ( = 0.101) or BAFO ( = 0.288). Within the limits of this study, 3D-printed implants without spikes and threaded implants showed comparable implant stability measurements, BIC, and BAFO.
螺纹种植体、无尖的三维（3D）打印种植体和有尖的3D打印种植体。在4只比格犬中，拔除左右下颌前磨牙（第2、3和4颗）及第一磨牙。12周后，将三种类型的钛种植体（螺纹种植体、无尖的3D打印种植体和有尖的3D打印种植体）随机植入每只犬的缺牙区牙槽嵴。种植体植入后每两周进行种植体稳定性测量和影像学记录。种植体手术后12周，处死犬只，比较各组之间的骨与种植体接触（BIC）和骨面积占有率（BAFO）。在种植体手术时，有尖的3D打印种植体的初始稳定性（74.05±5.61）低于螺纹种植体（83.71±2.90）（P = 0.005）。此后，直到术后第12周，各组之间种植体稳定性未观察到显著差异。组织形态计量学分析显示，三种种植体在BIC（P = 0.101）或BAFO（P = 0.288）方面未显示出显著差异。在本研究的范围内，无尖的3D打印种植体和螺纹种植体在种植体稳定性测量、BIC和BAFO方面表现相当。
